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Challenges presented by MERS corona virus, and SARS corona virus to global health
1Department of Family & Community Medicine, King Saud University, Saudi Arabia.
Abstract:
Numerous viral infections have arisen and affected global healthcare facilities. Millions of people are at severe risk of acquiring several evolving viral infections through several factors. In the present article we have described about risk factors, chance of infection, and prevention methods of Middle East Respiratory Syndrome Coronavirus (MERS-CoV) and severe acute respiratory syndrome (SARS-CoV), human coronaviruses (CoVs) frequently cause a normal cold which is mild and self-restricting. Zoonotic transmission of CoVs such as the newly discovered MERS-CoV and SARS-CoV, may be associated with severe lower respiratory tract infection. The present review provides the recent clinical and pathological information on MERS and SARS. The task is to transform these discoveries about MERS and SARS pathogenesis and to develop intervention methods that will eventually allow the effective control of these recently arising severe viral infections. Global health sector has learnt many lessons through the recent outbreak of MERS and SARS, but the need for identifying new antiviral treatment was not learned. In the present article we have reviewed the literature on the several facets like transmission, precautions and effectiveness of treatments used in patients with MERS-CoV and SARS infections.
Insights
This review details Middle East Respiratory Syndrome Coronavirus (MERS-CoV) and Severe Acute Respiratory Syndrome (SARS-CoV) risk factors, transmission, and prevention. It highlights the need for new antiviral treatments against these severe viral infections.
Area of Science:
- Virology
- Infectious Diseases
- Public Health
Background:
- Coronaviruses (CoVs) cause mild colds but zoonotic strains like MERS-CoV and SARS-CoV can lead to severe lower respiratory infections.
- Global healthcare faces risks from evolving viral infections, necessitating a deeper understanding of MERS and SARS.
- Past outbreaks have provided lessons, yet the development of novel antiviral therapies remains a critical unmet need.
Purpose of the Study:
- To review current clinical and pathological information on MERS and SARS.
- To identify risk factors, transmission routes, and effective prevention strategies for MERS-CoV and SARS-CoV.
- To emphasize the urgent need for developing new antiviral interventions against these emerging coronaviruses.
Main Methods:
- Literature review of MERS-CoV and SARS-CoV.
- Analysis of transmission dynamics and risk factors.
- Evaluation of current prevention and treatment effectiveness.
Main Results:
- MERS-CoV and SARS-CoV pose significant risks of severe lower respiratory tract infections.
- Understanding pathogenesis is key to developing effective control interventions.
- Current literature covers transmission, precautions, and treatment effectiveness for MERS and SARS.
Conclusions:
- Effective control of MERS and SARS requires translating research on pathogenesis into practical interventions.
- Continued vigilance and research into novel antiviral treatments are essential for global health security.
- Lessons from MERS and SARS outbreaks underscore the importance of preparedness against emerging viral threats.
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