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Intracystic Papillary Carcinoma in a Man with Gynecomastia
Radiology Case Reports
|June 16, 2016
Summary
This case report highlights intracystic papillary carcinoma in a male patient with gynecomastia. Early detection through mammography and ultrasound is crucial for diagnosis and favorable prognosis.
Area of Science:
- Oncology
- Radiology
Background:
- Male breast cancer is rare, while gynecomastia is common, with both linked to estrogen-to-androgen ratio.
- The association between gynecomastia and breast cancer is debated.
- Intracystic papillary carcinoma, traditionally ductal carcinoma in situ, may represent invasive malignancy based on immunohistochemistry.
Observation:
- A male patient with a history of gynecomastia presented with a breast lump.
- Mammography and ultrasound were used for diagnosis.
- Ultrasound revealed a complex mass, prompting further investigation.
Findings:
- Ultrasound-guided core needle biopsy diagnosed intracystic papillary carcinoma.
- Surgical excision confirmed the diagnosis.
- Intracystic papillary carcinoma generally has a favorable prognosis with local therapy.
Implications:
- This case underscores the importance of advanced imaging in diagnosing rare male breast cancers.
- It highlights the diagnostic utility of ultrasound in identifying complex breast masses.
- Accurate diagnosis of intracystic papillary carcinoma is key for appropriate and effective treatment planning.

