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Related Experiment Video

Updated: Mar 19, 2026

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Left Ventricular Function After Prolonged Exercise in Equine Endurance Athletes.

M Flethøj1, C C Schwarzwald2, M M Haugaard1

  • 1Department of Large Animal Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Taastrup, Denmark.

Journal of Veterinary Internal Medicine
|June 16, 2016
PubMed
Summary
This summary is machine-generated.

Prolonged endurance exercise impairs left ventricular diastolic function in horses, with reduced filling persisting hours after the event. These changes in cardiac function were not linked to hydration status.

Keywords:
Diastolic functionEchocardiographySpeckle trackingTissue Doppler imaging

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Area of Science:

  • Equine cardiology
  • Exercise physiology
  • Veterinary sports medicine

Background:

  • Human athletes experience transient left ventricular (LV) dysfunction, termed cardiac fatigue, after prolonged exercise.
  • The cardiac effects of extended physical exertion in horses are not well understood.

Purpose of the Study:

  • To investigate the impact of prolonged exercise on LV systolic and diastolic function in horses.
  • To assess cardiac function changes in horses participating in endurance rides.

Main Methods:

  • A cross-sectional field study involving 26 horses during 120-160 km endurance rides.
  • Echocardiography, including 2D, M-mode, tissue Doppler, and speckle tracking, was performed before, immediately after, and the morning following the rides.
  • Evaluated correlations between echocardiographic variables and cardiac troponin I concentrations.

Main Results:

  • Significant decreases in early diastolic myocardial velocities were observed in both longitudinal and radial directions post-exercise.
  • Early diastolic strain rates significantly declined in longitudinal and circumferential directions after prolonged exercise.
  • Systolic function variables yielded ambiguous results, and no correlation was found between cardiac function changes and serum cardiac troponin I levels.

Conclusions:

  • Prolonged exercise in horses is associated with impaired LV diastolic function, characterized by reduced ventricular filling.
  • These diastolic impairments persisted for 7-21 hours post-exercise, independent of hydration status.
  • The clinical significance and long-term implications of this exercise-induced cardiac fatigue in horses require further investigation.