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Rabbit brown adipose tissue uncoupling protein MRNA: use of only one of two polyadenylation signals in its processing
A G Balogh1, R G Ridley, H V Patel
1Department of Biochemistry, McMaster University, Hamilton, Ontario, Canada.
Biochemical and Biophysical Research Communications
|May 30, 1989
Abstract:
A cDNA containing the complete coding sequence of rabbit brown adipose tissue uncoupling protein was isolated and sequenced. The coding region is 80.6% identical to rat UCP cDNA and the protein is about 86% identical to the rat and hamster proteins. Despite the presence of 2 AATAAA polyadenylation consensus sequences in rabbit UCP cDNA, only one rabbit UCP mRNA was detected indicating that only the 3'-downstream signal is used in contrast to rat and mouse where both are used.