Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Substance Use Disorders Affecting Sleep01:24

Substance Use Disorders Affecting Sleep

522
Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
Understanding the concepts of physical dependence,...
522
Drug Dependence01:17

Drug Dependence

1.9K
Medications are typically administered to achieve therapeutic effects. Some drugs can modify an individual's mood and perception, frequently resulting in various enjoyable experiences. However, this can result in drug dependency, a condition marked by continuous drug use despite potential negative consequences. Drug dependency primarily falls into two categories: psychological and physical dependence. Psychological dependence occurs when the pleasurable feelings induced by the drug...
1.9K
Drug Abuse and Addiction: Pharmacological Phenomena01:15

Drug Abuse and Addiction: Pharmacological Phenomena

1.4K
Drug dependence, abuse, and addiction are complex phenomena that can precipitate various abnormal states. Physical dependence refers to a state of pharmacological adaptation to a drug. This adaptation often results in tolerance—a reduced response to the drug after repeated administrations. When the drug use is abruptly stopped, withdrawal symptoms occur due to the body's need to readjust from the pharmacologically induced imbalance. However, tolerance and withdrawal symptoms do not...
1.4K
Cognitive Enhancers: Cholinesterase Inhibitors and NMDA Receptor Antagonists01:30

Cognitive Enhancers: Cholinesterase Inhibitors and NMDA Receptor Antagonists

807
Cognitive enhancers, also known as "smart drugs," are substances used to enhance memory, mental alertness, and concentration. These can be natural or synthetic and improve cognition in conditions like Alzheimer's disease (AD) and other neurodegenerative diseases. Some common examples include caffeine, amphetamines, methylphenidate, modafinil, arecoline, donepezil, vortioxetine, and piracetam. These enhancers work on the principle of synaptic plasticity and altered circuit function.
807
Stimulants01:29

Stimulants

1.2K
Stimulants are substances that enhance neural activity and elevate dopamine levels in the brain, leading to their highly addictive nature. These drugs include cocaine, amphetamines, MDMA, caffeine, and nicotine, each with distinct mechanisms of action and varied health implications.
Cocaine can be administered via snorting, injection, or smoking. It primarily functions by blocking the reuptake of dopamine, resulting in a euphoric high characterized by an intense sensation of happiness and...
1.2K
Drug Control Governance: Regulatory Bodies and Their Impact01:03

Drug Control Governance: Regulatory Bodies and Their Impact

639
Drug control governance involves the oversight and regulation of pharmaceuticals to ensure their safety and efficacy while preventing illegal drug use and trafficking. Regulatory bodies, including the US Food and Drug Administration (FDA) and the European Union's European Medicines Agency (EMA), play a central role in this process. These agencies evaluate the safety and efficacy of drugs before they can be marketed. They fund clinical trials and assess the benefits and risks associated with...
639

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Sex Differences in the Development of a Multidimensional Fall Risk Index for Older Adults.

Gerontology·2026
Same author

Cannabis retail environment and treatment for cannabis use disorder.

Drug and alcohol dependence·2026
Same author

Rural and Urban Variation in Mobile Health Substance Use Disorder Treatment Mechanisms and Efficacy.

Rural mental health·2026
Same author

The age of eczema onset and multiple food allergies.

Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology·2025
Same author

Prospective associations of subjective and objective neighborhood disadvantage with cannabis and nicotine vaping among Southern California adolescents.

Health & place·2025
Same author

Associations between asthma and the risk of mental and behavioral problems in males.

The Journal of asthma : official journal of the Association for the Care of Asthma·2025
Same journal

Opioid use disorder and hospital readmission in the United States from 2010 to 2022: Primary reasons and the complex interplay of comorbid conditions.

Drug and alcohol dependence·2026
Same journal

Impact of medicaid waivers on medication for opioid use disorders in residential facilities: Evidence from twenty-five states.

Drug and alcohol dependence·2026
Same journal

Mental and somatic multimorbidity among individuals with alcohol use disorder: A sex-stratified registry study.

Drug and alcohol dependence·2026
Same journal

Monitoring novel psychoactive substance trends on social media: Analysis of discussions and dashboard implementation.

Drug and alcohol dependence·2026
Same journal

A meta-analysis on the relationship between cultural identity and substance use among indigenous youth.

Drug and alcohol dependence·2026
Same journal

Examining heterogeneity in pathways between alcohol-related factors and drinking during topiramate pharmacotherapy: A person-specific analysis.

Drug and alcohol dependence·2026
See all related articles

Related Experiment Video

Updated: Mar 19, 2026

A Computerized Functional Skills Assessment and Training Program Targeting Technology Based Everyday Functional Skills
07:31

A Computerized Functional Skills Assessment and Training Program Targeting Technology Based Everyday Functional Skills

Published on: February 13, 2020

7.5K

Improving substance use prevention efforts with executive function training.

Mary Ann Pentz1, Nathaniel R Riggs2, Christopher M Warren1

  • 1The Institute for Health Promotion & Disease Prevention Research (IPR), Department of Preventive Medicine, University of Southern California, Keck School of Medicine, Los Angeles, CA 90032 USA.

Drug and Alcohol Dependence
|June 17, 2016
PubMed
Summary
This summary is machine-generated.

Targeting inhibitory control (IC), a key executive function (EF), is crucial for youth substance use (SU) prevention. Integrating mindfulness training with EF programs may further enhance prevention efforts.

Keywords:
AdolescentDrug abuse preventionEmotional regulationExecutive functionImpulse controlInhibitory controlMindfulness

More Related Videos

A Prediction Error-driven Retrieval Procedure for Destabilizing and Rewriting Maladaptive Reward Memories in Hazardous Drinkers
08:05

A Prediction Error-driven Retrieval Procedure for Destabilizing and Rewriting Maladaptive Reward Memories in Hazardous Drinkers

Published on: January 5, 2018

10.3K
Working Memory Training for Older Participants: A Control Group Training Regimen and Initial Intellectual Functioning Assessment
07:01

Working Memory Training for Older Participants: A Control Group Training Regimen and Initial Intellectual Functioning Assessment

Published on: September 20, 2020

5.3K

Related Experiment Videos

Last Updated: Mar 19, 2026

A Computerized Functional Skills Assessment and Training Program Targeting Technology Based Everyday Functional Skills
07:31

A Computerized Functional Skills Assessment and Training Program Targeting Technology Based Everyday Functional Skills

Published on: February 13, 2020

7.5K
A Prediction Error-driven Retrieval Procedure for Destabilizing and Rewriting Maladaptive Reward Memories in Hazardous Drinkers
08:05

A Prediction Error-driven Retrieval Procedure for Destabilizing and Rewriting Maladaptive Reward Memories in Hazardous Drinkers

Published on: January 5, 2018

10.3K
Working Memory Training for Older Participants: A Control Group Training Regimen and Initial Intellectual Functioning Assessment
07:01

Working Memory Training for Older Participants: A Control Group Training Regimen and Initial Intellectual Functioning Assessment

Published on: September 20, 2020

5.3K

Area of Science:

  • Neuroscience
  • Developmental Psychology
  • Public Health

Background:

  • Executive function (EF) encompasses emotional regulation, planning, and impulse control, crucial for adolescent development.
  • Youth substance use (SU) prevention strategies face challenges in identifying specific EF sub-domains and SU types linked to risk.
  • The potential of mindfulness training to enhance EF-based SU prevention programs requires further investigation.

Purpose of the Study:

  • To determine which executive function (EF) sub-domains are most strongly associated with youth substance use (SU).
  • To investigate the relationship between specific EF sub-domains and different types of SU.
  • To explore the potential benefits of incorporating mindfulness training into EF-focused SU prevention programs.

Main Methods:

  • Data from two studies (RCT and cross-sectional pilot) involving 4th-7th graders were analyzed.
  • Measures included assessments of inhibitory control (IC), emotional control, working memory, organization/planning, lifetime SU (tobacco, alcohol), and mindfulness.
  • Multivariate and multiple group path analyses were employed to examine relationships.

Main Results:

  • Inhibitory control (IC) emerged as the most consistent predictor of SU, particularly for cigarette and e-cigarette use.
  • Emotional control predicted alcohol use in late-elementary students.
  • In 7th graders, IC predicted substance use only in those with lower mindfulness levels.

Conclusions:

  • Enhancing substance use (SU) prevention may involve increased curriculum focus on inhibitory control (IC) and its application.
  • Systematically integrating mindfulness with executive function (EF) skills training holds promise for improved prevention outcomes.
  • Future research should explore how EF-SU relationships vary across different SU patterns and assessment methods.