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Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
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Related Experiment Video

Updated: Mar 19, 2026

Leveraging Turbidity and Thromboelastography for Complementary Clot Characterization
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Thromboelastography: Clinical Application, Interpretation, and Transfusion Management.

Shawn Collins, Carolyn MacIntyre, Ian Hewer

    AANA Journal
    |June 18, 2016
    PubMed
    Summary

    Thromboelastography offers a comprehensive assessment of blood coagulation, including platelet function, unlike traditional tests. This advanced method aids surgical patients by providing a clearer picture of hemostatic status for better management.

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    Area of Science:

    • Coagulation Science
    • Hemostasis and Thrombosis
    • Surgical Transfusion Management

    Background:

    • The coagulation cascade is a complex process involving primary and secondary hemostasis, platelet function, thrombin generation, and fibrinolysis.
    • Accurate assessment of coagulation is crucial for managing hemostatic issues in surgical patients.
    • Traditional coagulation tests (e.g., platelet count, PT, aPTT) offer valuable data but do not measure platelet function.

    Purpose of the Study:

    • To highlight the limitations of traditional coagulation monitoring in surgical settings.
    • To introduce thromboelastography as a superior method for assessing whole blood coagulation.
    • To emphasize the importance of evaluating platelet function in surgical hemostasis management.

    Main Methods:

    • Review of traditional coagulation tests used in surgical transfusion management.
    • Introduction of thromboelastography (TEG) as a method for assessing whole blood coagulation.
    • Comparison of TEG's capabilities with traditional tests, focusing on platelet function assessment.

    Main Results:

    • Traditional coagulation tests provide limited information, notably lacking platelet function assessment.
    • Thromboelastography measures whole blood coagulation, integrating platelet function and other critical factors.
    • TEG offers a more comprehensive understanding of a patient's hemostatic status compared to conventional methods.

    Conclusions:

    • Thromboelastography addresses the deficit in traditional coagulation monitoring by including platelet function.
    • This comprehensive assessment is critical for guiding appropriate product selection and transfusion management in surgical patients.
    • Thromboelastography provides a more complete picture of coagulation, considering factors like platelet function and temperature.