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Updated: Mar 19, 2026

Rapid Viscoelastic Characterization of Airway Mucus Using a Benchtop Rheometer
Published on: April 21, 2022
Different macro- and micro-rheological properties of native porcine respiratory and intestinal mucus
Harish Bokkasam1, Matthias Ernst2, Marco Guenther2
1Department of Pharmacy, Saarland University, D-66123 Saarbrücken, Germany.
Abstract:
Aim of this study was to investigate the similarities and differences at macro- and microscale in the viscoelastic properties of mucus that covers the epithelia of the intestinal and respiratory tract. Natural mucus was collected from pulmonary and intestinal regions of healthy pigs. Macro-rheological investigations were carried out through conventional plate-plate rheometry. Microrheology was investigated using optical tweezers. Our data revealed significant differences both in macro- and micro-rheological properties between respiratory and intestinal mucus.
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