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Updated: Mar 19, 2026

In Situ Hybridization in Zebrafish Larvae and Juveniles during Mesonephros Development

In Situ Hybridization in Zebrafish Larvae and Juveniles during Mesonephros Development

Published on: August 13, 2021

Zebrafish kidney development.

I A Drummond¹, A J Davidson²

¹Massachusetts General Hospital, Charlestown, MA, United States.

Methods in Cell Biology

|June 18, 2016

Summary

This summary is machine-generated.

Zebrafish pronephros development offers insights into vertebrate kidney organogenesis. This review covers advances in studying kidney cell types, function, and regeneration in zebrafish.

Keywords:

Kidney Nephron Organogenesis Pronephros Regeneration

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Analysis of Nephron Composition and Function in the Adult Zebrafish Kidney

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Last Updated: Mar 19, 2026

In Situ Hybridization in Zebrafish Larvae and Juveniles during Mesonephros Development

In Situ Hybridization in Zebrafish Larvae and Juveniles during Mesonephros Development

Published on: August 13, 2021

Analysis of Zebrafish Kidney Development with Time-lapse Imaging Using a Dissecting Microscope Equipped for Optical Sectioning

Analysis of Zebrafish Kidney Development with Time-lapse Imaging Using a Dissecting Microscope Equipped for Optical Sectioning

Published on: April 7, 2016

Analysis of Nephron Composition and Function in the Adult Zebrafish Kidney

Analysis of Nephron Composition and Function in the Adult Zebrafish Kidney

Published on: August 9, 2014

Area of Science:

Developmental Biology
Comparative Anatomy
Renal Physiology

Background:

The zebrafish pronephros shares significant similarities with human kidneys in cell types and developmental processes.
These conserved features establish the zebrafish as a powerful model organism for studying kidney development and disease.
Understanding pronephric development is crucial for advancing regenerative medicine and treating kidney disorders.

Purpose of the Study:

To review recent advancements in zebrafish pronephric development research.
To provide practical experimental protocols for analyzing kidney structures and functions in zebrafish.
To explore the mechanisms underlying kidney regeneration in response to injury using zebrafish models.

Main Methods:

Literature review of recent studies on zebrafish pronephric development.
Description of protocols for analyzing kidney cell types and tissue architecture.
Explanation of methods for measuring nephron function and in vivo imaging of kidney cells.
Outline of techniques to investigate kidney regeneration mechanisms.

Main Results:

Recent studies have elucidated key cellular and molecular mechanisms governing zebrafish kidney organogenesis.
Established protocols enable detailed analysis of kidney cell types, nephron structure, and overall kidney function.
Zebrafish models are instrumental in dissecting the cellular basis of kidney regeneration after injury.

Conclusions:

The zebrafish pronephros serves as an excellent model for understanding fundamental principles of vertebrate kidney development and regeneration.
The reviewed protocols facilitate comprehensive investigation into kidney biology and disease modeling.
Further research in zebrafish promises to yield significant insights into human kidney development and therapeutic strategies for kidney diseases.