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Cerebral Microhemorrhages: Significance, Associations, Diagnosis, and Treatment

Eric Jouvent1, Laurent Puy1, Hugues Chabriat2

  • 1Univ Paris Diderot, UMR-S 1161 INSERM and DHU NeuroVasc Sorbonne Paris Cité and AP-HP, Lariboisière Hosp, Department of Neurology, 2 rue Ambroise Paré, 75010, Paris, France.

Current Treatment Options in Neurology
|June 18, 2016
PubMed

Insights

Cerebral microhemorrhages (CMs) are increasingly detected with brain MRI and help assess hemorrhagic versus ischemic risks. Integrating CM data into personalized medicine will improve patient management for cerebrovascular diseases.

Area of Science:

  • Neurology
  • Radiology
  • Vascular Medicine

Background:

  • Cerebrovascular pathologies present both ischemic and hemorrhagic risks, particularly in aging populations.
  • Brain magnetic resonance imaging (MRI) is a primary tool for evaluating cerebrovascular diseases.
  • Cerebral microhemorrhages (CMs) are small foci of signal loss on MRI, initially considered imaging artifacts.

Purpose of the Study:

  • To review the evolving understanding of cerebral microhemorrhages (CMs).
  • To highlight the role of CMs in estimating hemorrhagic versus ischemic risks.
  • To discuss the integration of CMs into personalized patient management for cerebrovascular diseases.

Main Methods:

  • Review of research studies on cerebral microhemorrhages (CMs) over the past 20 years.
  • Analysis of the clinical significance of CMs detected via brain MRI.
  • Exploration of the potential for CMs in personalized medicine.

Main Results:

  • CMs are now recognized as indicators of small vessel rupture, not just imaging artifacts.
  • CMs provide valuable information for assessing the balance between hemorrhagic and ischemic risks.
  • The number and location of CMs offer crucial data for clinical decision-making.

Conclusions:

  • Cerebral microhemorrhages (CMs) are significant imaging biomarkers in cerebrovascular diseases.
  • Understanding CMs is essential for personalized treatment strategies.
  • Integrating CM assessment into patient management is critical for future clinical practice.
Abstract

Keywords:
AntithromboticsCerebral microhemorrhageIntracerebral hemorrhageIschemic strokeMRI

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