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Related Concept Videos

Angle Closure Glaucoma: Treatment01:28

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Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
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In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
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Related Experiment Video

Updated: Mar 19, 2026

Three Different Protocols of Corneal Collagen Crosslinking in Keratoconus: Conventional, Accelerated and Iontophoresis
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Three Different Protocols of Corneal Collagen Crosslinking in Keratoconus: Conventional, Accelerated and Iontophoresis

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[Crosslinking in Keratoconus].

S J Lang1, T Reinhard1

  • 1Klinik für Augenheilkunde, Universitätsklinikum Freiburg.

Klinische Monatsblatter Fur Augenheilkunde
|June 18, 2016
PubMed
Summary
This summary is machine-generated.

Corneal crosslinking can halt keratoconus progression, but not all patients benefit. Avoid this procedure for patients without progression to prevent risks like scarring and infection.

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Area of Science:

  • Ophthalmology
  • Corneal Diseases
  • Surgical Innovation

Background:

  • Keratoconus is a progressive corneal disease causing thinning and protrusion.
  • Younger patients are at higher risk for keratoconus progression.
  • Corneal crosslinking (CXL) aims to halt this progression.

Purpose of the Study:

  • To evaluate the efficacy and risks of corneal crosslinking for keratoconus.
  • To determine if all keratoconus patients benefit from CXL.
  • To establish criteria for appropriate CXL patient selection.

Main Methods:

  • Review of six randomized controlled trials (RCTs) on corneal crosslinking.
  • Analysis of keratometric data to assess treatment efficacy.
  • Evaluation of reported adverse events and patient progression post-CXL.

Main Results:

  • RCTs confirm the efficacy of CXL in halting keratoconus progression based on keratometric data.
  • Progression was observed in a subset of patients who received CXL in two trials.
  • Identified risks include corneal scarring, haze, endothelial cell damage, and infection.

Conclusions:

  • Corneal crosslinking is effective for many keratoconus patients.
  • Not all patients achieve cessation of progression with CXL.
  • To mitigate risks, CXL should be reserved for patients with documented keratoconus progression.