Emerging infectious diseases with cutaneous manifestations: Viral and bacterial infections

Zeena Y Nawas1, Yun Tong1, Ramya Kollipara2

  • 1Center for Clinical Studies, Houston, Texas.

Insights

Emerging bacterial and viral infections are increasing globally. This review details their skin symptoms, diagnosis, and treatment to improve patient outcomes.

Area of Science:

  • Infectious Diseases
  • Dermatology
  • Global Health

Background:

  • Increased international travel, immigration, and climate change are driving the emergence of previously uncommon bacterial and viral infections in the Western Hemisphere.
  • Delayed diagnosis and treatment of these emerging infections can result in significant patient morbidity and mortality.
  • A lack of dermatology literature on the cutaneous manifestations of these diseases contributes to inconsistent diagnosis and management.

Purpose of the Study:

  • To review the epidemiology, cutaneous manifestations, diagnosis, and management of emerging bacterial and viral diseases.
  • To provide a comprehensive resource for clinicians managing these infections.
  • To improve the consistency and effectiveness of patient care for emerging infectious diseases.

Main Methods:

  • Literature review focusing on epidemiology, clinical presentation, diagnostic approaches, and treatment strategies.
  • Synthesis of information on bacterial and viral infections with significant cutaneous manifestations.
  • Analysis of current management guidelines and recommendations.

Main Results:

  • Detailed description of the epidemiology of key emerging infectious diseases.
  • Comprehensive overview of characteristic skin findings for various bacterial and viral pathogens.
  • Discussion of diagnostic challenges and recommended diagnostic tools.
  • Summary of current therapeutic options and management protocols.

Conclusions:

  • Emerging infectious diseases pose a growing threat, necessitating increased awareness and preparedness.
  • Understanding the dermatologic manifestations is crucial for early recognition and diagnosis.
  • Standardized diagnostic and management approaches are needed to mitigate patient morbidity and mortality.

Related Concept Videos

Skin Diseases and Disorders01:23

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
6.1K
Staphylococcal Skin Infections01:29

Staphylococcal Skin Infections

Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...
4
Infection01:20

Infection

When a pathogen enters the body and reproduces, it can cause an infection, damage body cells, and cause illness symptoms that eventually lead to disease. Therefore, its prevention requires breaking the chain of infection.
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
14.0K
Infectious Diseases and Their Occurrence01:28

Infectious Diseases and Their Occurrence

Infectious diseases appear in populations through various transmission patterns, influenced by pathogen characteristics, population immunity, environmental conditions, and social behavior. Understanding these patterns is essential for effective public health surveillance and intervention. These categories—sporadic, outbreak, epidemic, pandemic, and endemic—help frame the nature and scope of disease events.Sporadic diseases occur irregularly and infrequently, without a predictable...
25
Sexually Transmitted Infections01:26

Sexually Transmitted Infections

Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
1.5K
Viral Meningitis01:18

Viral Meningitis

Viral meningitis is the most common form of meningitis and is often referred to as aseptic meningitis to indicate the absence of bacterial involvement. It is generally milder than bacterial meningitis, with symptoms including fever, headache, stiff neck, drowsiness, nausea, photophobia, and vomiting. Rarely, more severe manifestations or death may occur. Common causative agents include enteroviruses, particularly coxsackie A and B viruses and echoviruses, all members of the Enterovirus genus...
2