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Updated: Aug 14, 2026

A Model to Simulate Clinically Relevant Hypoxia in Humans
Published on: December 22, 2016
An in vitro tissue model for evaluating the effect of carboxyhemoglobin concentration on pulse oximetry
Abstract:
An in vitro tissue model was developed for specific application to noninvasive transmittance pulse oximetry. The model was used to assess the effect of variations in carboxyhemoglobin concentration on noninvasive measurements of arterial hemoglobin oxygen saturation. The predictive nature of this model is important for a better understanding of the limitation of pulse oximetry and for the improved design of pulse oximeters.
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