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PET/Computed Tomography in Breast Cancer: Can It Aid in Developing a Personalized Treatment Design?
Sumeet Suresh Malapure1, Kalpa Jyoti Das2, Rakesh Kumar2
1Department of Nuclear Medicine, Kasturba Medical College, Manipal University, SH 65, Manipal 576104, Karnataka, India.
Abstract:
PET with fluorodeoxyglucose (FDG-PET)/computed tomography (CT) imaging has significantly improved the management of breast cancer. FDG, however, is not tumor-specific and various image interpretation pitfalls may occur due to false-positive and false-negative causes of FDG uptake. PET/CT imaging with more specific radiopharmaceuticals may provide useful information about the pathophysiology in such cases. In the present article, we reviewed the use of whole-body FDG-PET/CT and (18)F-16α-17β-Fluoroestradiol PET/CT imaging to determine if these can be used to develop personalized treatment design for the better management of breast cancer.
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