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Updated: Mar 19, 2026

Use of 3D Robotic Ultrasound for In Vivo Analysis of Mouse Kidneys
Published on: August 12, 2021
An Automated Approach for Kidney Segmentation in Three-Dimensional Ultrasound Images
Abstract:
Automated segmentation of kidneys in three-dimensional (3-D) abdominal ultrasound volumes is a task of paramount importance in automated diagnosis of abdominal trauma. However, ultrasound speckle noise, low-contrast boundaries, partial kidney occlusion, and probe misalignment restrict the utility of the solution, especially when it is used in emergency rooms and Focused Assessment with Sonography Trauma applications. This paper introduces a systematic and cost-effective method capable of detecting and segmenting the kidney's shape in acquired 3-D ultrasound volumes, using off-line training datasets. This paper offers a new shape model representation, called the complex-valued implicit shape model, to generate a 3-D kidney shape model by combining prior knowledge of training shapes and anatomical knowledge. We apply shape-to-volume registration, based on a new similarity metric, to detect the kidney shape by fitting the 3-D shape model on 3-D ultrasound volumes. Upon kidney detection, the fitted shape model is used to initialize and evolve a new level-set function, called complex-valued rational level-set with shape prior, to segment the kidney's shape. Experimentation using both simulated and actual ultrasound volumes indicate that the proposed solution provides a better performance over the state-of-the-art volumetric ultrasound segmentation methods.
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