ASSOCIATION OF MATERNAL PERIODONTITIS WITH LOW BIRTH WEIGHT IN NEWBORNS IN A TERTIARY CARE HOSPITAL

Insights

Maternal periodontitis significantly increases the risk of low birth weight in newborns. Periodontal therapy is recommended as part of antenatal care to mitigate this risk.

Area of Science:

  • Public Health
  • Periodontology
  • Obstetrics

Background:

  • Low birth weight (LBW) is a significant public health concern in Pakistan.
  • Identifying modifiable risk factors like periodontitis is crucial for reducing the burden of LBW.
  • This study investigated the association between maternal periodontitis and LBW in Abbottabad.

Purpose of the Study:

  • To determine the association between maternal periodontitis and low birth weight in newborns.
  • To assess the frequency and severity of periodontitis in mothers delivering LBW babies.
  • To identify periodontitis as a potential modifiable risk factor for LBW.

Main Methods:

  • A hospital-based matched case-control study was conducted with 160 postpartum mothers.
  • 80 mothers of LBW babies (cases) were matched with 80 mothers of normal birth weight babies (controls) by age and gestational age.
  • Data collection involved hospital records, interviews, and periodontal examinations.

Main Results:

  • Periodontitis was significantly more prevalent in mothers of LBW babies (OR: 4.167).
  • Multivariate analysis confirmed periodontitis as an independent risk factor for LBW (aOR: 3.173).
  • Other independent risk factors included lower educational level, socioeconomic status, poor maternal nutrition, and moderate/severe anemia.

Conclusions:

  • Maternal periodontitis is a strong, independent, and clinically significant risk factor for low birth weight.
  • Periodontal therapy should be integrated into antenatal care protocols for pregnant women.
  • Addressing periodontitis may help reduce the incidence of LBW in the region.
Abstract

Related Concept Videos

Development of the Oral Microbiota01:28

Development of the Oral Microbiota

The establishment of the oral microbiome begins before birth, challenging the long-held belief that the fetal oral cavity is sterile. The presence of oral microbes such as Streptococcus and Fusobacterium in amniotic fluid suggests that microbial exposure may occur in utero, potentially through translocation from the maternal oral or gastrointestinal tract. This early colonization primes the neonatal immune system and sets the stage for subsequent microbial succession. Maternal health,...
7
The Oral Microbiota01:27

The Oral Microbiota

The oral microbiome includes a complex ecosystem comprising over 700 microbial species, identified through genomic sequencing and culture-based analyses to date. This community includes a core microbiome, found universally among individuals, and a variable component influenced by environmental factors such as diet, lifestyle, and host genetics. Site-specific conditions, including oxygen gradients, pH levels, and nutrient availability, determine the spatial distribution of these microorganisms...
7
Pathophysiology of Diabetes01:20

Pathophysiology of Diabetes

Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
4.2K
Development of Human Microbiota01:30

Development of Human Microbiota

The human microbiota begins developing at birth and undergoes continual change as we age. Infancy marks a critical period of microbial sensitivity, offering a “window of opportunity” during which beneficial microbes help mature the immune system. By age three, children typically develop a more stable and diverse microbial community. Newborns acquire microbes from their immediate environment; vaginal delivery favors maternal vaginal microbes, while cesarean births favor microbes from...
5
Teeth01:15

Teeth

The formation of teeth, also known as odontogenesis, is a complex process that begins in utero, around the sixth week of embryonic development. There are three stages to this process: the bud stage, the cap stage, and the bell stage.
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...
2.1K