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Updated: Mar 19, 2026

Transcutaneous Microcirculatory Imaging in Preterm Neonates
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[A follow-up on first-year growth and development of 61 very low birth weight preterm infants]

Ying Deng1, Fei Xiong, Meng-Meng Wu

  • 1Department of Pediatrics, West China Second University Hospital, Sichuan University, Chengdu 610041, China. 506742295@qq.com.

Zhongguo Dang Dai Er Ke Za Zhi = Chinese Journal of Contemporary Pediatrics
|June 22, 2016
PubMed

Insights

Very low birth weight (VLBW) preterm infants show significant growth deviations early on. A high percentage of these infants experience abnormal development in their first year, with small-for-gestational-age status being a key risk factor.

Area of Science:

  • Neonatalogy and Pediatrics
  • Developmental Biology
  • Public Health

Context:

  • Preterm birth, particularly very low birth weight (VLBW), presents significant challenges for infant development.
  • Early monitoring of physical growth and psychomotor development is crucial for identifying potential issues in VLBW infants.

Purpose:

  • To investigate the physical growth and psychomotor development of very low birth weight (VLBW) preterm infants during their first year of life.
  • To identify factors influencing the growth and development trajectories of these vulnerable infants.

Summary:

  • This study monitored 61 VLBW preterm infants for 12 months using Z-scores for growth and the Denver Development Screen Test (DDST) for development.
  • While median growth parameters remained above -1 SD, specific incidence rates for various growth deviations were noted by 40 weeks corrected age.
  • By one year, 25% of infants had abnormal developmental quotients (DQ), with small-for-gestational-age (SGA) infants showing a higher incidence of abnormal DQ and being an independent risk factor for retarded growth.

Impact:

  • VLBW infants exhibit notable growth deviations within the first three months of corrected age.
  • The high prevalence of abnormal developmental quotients (DQ) identified by DDST highlights the need for ongoing developmental surveillance in VLBW populations.
  • Findings underscore the critical role of SGA status as a predictor of impaired growth in VLBW preterm infants, informing targeted interventions.
Abstract

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