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Updated: Mar 19, 2026
06:38
Determination of Reproductive Competence by Confirming Pubertal Onset and Performing a Fertility Assay in Mice and Rats
Published on: October 13, 2018
16.5K
[Cryptorchidism and fertility]
1Sektion für Kinder- und Jugendurologie an der Klinik für Urologie, Universitätsklinikum Essen, Hufelandstraße 55, 45122, Essen, Deutschland. iris.ruebben@uk-essen.de.
Der Urologe. Ausg. A
|June 22, 2016
Summary
Cryptorchidism, a common genital malformation, impacts male fertility. Early intervention is crucial as untreated cases can lead to azoospermia (absence of sperm) and infertility later in life.
Area of Science:
- Pediatric Urology
- Reproductive Medicine
Background:
- Cryptorchidism is the most common genital malformation in pediatric urology.
- Affects 1% of full-term male infants unilaterally and 20% bilaterally within the first year of life.
Purpose of the Study:
- To identify factors influencing postpubertal spermatogenesis in relation to early-life development.
- To summarize current knowledge on cryptorchidism and its long-term reproductive outcomes.
Main Methods:
- Literature review and knowledge synthesis.
- Analysis of epidemiological data and clinical outcomes related to cryptorchidism.
Main Results:
- Azoospermia affects 10% of men with unilateral and 32% with bilateral cryptorchidism.
- 10-20% of men diagnosed with infertility have a history of orchiopexy (surgical correction).
Conclusions:
- Early-life factors in cryptorchidism significantly influence postpubertal spermatogenesis.
- Untreated or delayed treatment of cryptorchidism is associated with increased risks of male infertility and azoospermia.
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