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Updated: Mar 19, 2026

Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function
Published on: March 15, 2022
The role of coronary CT angiography in chronic total occlusion intervention
Stephen C W Cheung1, Michael C L Lim2, Carmen W S Chan3
1Department of Radiology, Queen Mary Hospital, HKSAR, PR China.
Insights
Coronary CT angiography (CCTA) aids in planning percutaneous coronary intervention (PCI) for chronic total occlusions (CTOs). This imaging helps predict procedural success and reduce complications, improving patient outcomes.
Area of Science:
- Cardiovascular Imaging
- Interventional Cardiology
Background:
- Percutaneous coronary intervention (PCI) for chronic total occlusions (CTOs) presents significant technical challenges.
- Lack of visual guidance during PCI for CTOs increases risks of arterial dissection, perforation, and cardiac tamponade.
Purpose of the Study:
- To evaluate the role of coronary CT angiography (CCTA) in managing CTOs.
- To assess CCTA's ability to identify CTOs, predict revascularization benefits, and aid procedural planning.
Main Methods:
- Utilisation of multidetector CT technology for coronary CT angiography (CCTA).
- Analysis of CCTA for CTO identification, location, and assessment of potential revascularization benefits.
Main Results:
- CCTA is crucial for identifying CTO presence and location.
- CCTA assists in predicting clinical benefits of revascularization and aids in preprocedural planning.
- CCTA helps visualize the procedure, predict crossing difficulty, and estimate complication frequency.
Conclusions:
- CCTA is valuable for preprocedural planning in CTO PCI, improving safety and efficiency.
- CCTA facilitates postprocedural assessment and long-term follow-up of stented segments.
Abstract:
Revascularisation by percutaneous coronary intervention (PCI) in chronic total occlusion (CTO) is often a technically challenging procedure. The manipulation of wires and devices through a CTO during PCI without any means to visually identify vessel-wall boundaries involves an inherent risk of complications such as arterial dissection, perforation and cardiac tamponade. With the tremendous advances in multidetector CT technology and the popularity of utilising coronary CT angiogram (CCTA) for a workup of chest pain patients, an increasing number of CTO cases are being encountered. Therefore, the primary goal of CCTA for imaging in CTOs involves identifying the presence and locations of CTO as well as predicting the potential clinical benefits derived from revascularisation of the occluded segment. The secondary goal includes preprocedural planning to shorten procedure times, visualisation of the procedure in predicting the ease with which a CTO can be crossed and the frequency of procedure-related complications such as contrast nephropathy and radiation skin injury. Apart from these, CCTA also plays a role in postprocedural assessment of the revascularised arterial segments and long-term follow-up on the patency of coronary stents.
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