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Interferon-α and pericardial injury: a case report and literature review

Fayaz A Hakim1, Sujata Singh2, Anil Pandit1

  • 1Department of Cardiovascular Diseases, Scottsdale, Arizona , USA.

Heart Asia
|June 22, 2016
PubMed

Interferon- α (IFN-α) alone or in combination with other chemotherapeutic agents has been used in the management of many malignant and non-malignant conditions. Pericarditis with or without pericardial effusion has been reported with IFN-α therapy, and available literature is limited to case reports. Pericardial constriction after interferon use has not been described in the published literature to date. We performed a systematic review of literature to address the demographic features, clinical presentation, diagnosis, treatment and outcome of interferon-related pericardial injury.

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