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Comparison of a supplemented Rose Questionnaire to exercise thallium testing in men and women

E B Bass1, W P Follansbee, T J Orchard

  • 1Department of Epidemiology, University of Pittsburgh, PA 15261.

Journal of Clinical Epidemiology
|January 1, 1989
PubMed

Insights

The Rose Questionnaire shows low sensitivity for diagnosing angina pectoris and myocardial infarction. Supplementing the questionnaire improved sensitivity but reduced specificity for coronary artery disease detection.

Area of Science:

  • Cardiology
  • Diagnostic Accuracy

Background:

  • The Rose Questionnaire is a tool for identifying angina pectoris symptoms.
  • Its accuracy, particularly sensitivity, has been a point of concern compared to physician diagnosis.

Purpose of the Study:

  • To evaluate the accuracy of a supplemented Rose Questionnaire.
  • To compare questionnaire results against exercise thallium test evidence for coronary artery disease.

Main Methods:

  • A series of 198 patients were assessed using a supplemented Rose Questionnaire.
  • Questionnaire diagnoses were compared with exercise thallium test results.

Main Results:

  • The standard Rose Questionnaire showed low sensitivity (26%) for angina and myocardial infarction.
  • Supplementation increased sensitivity up to 68% but decreased specificity.
  • Women showed higher sensitivity but lower specificity than men for coronary disease.

Conclusions:

  • The Rose Questionnaire, even supplemented, has limitations in accurately diagnosing coronary artery disease.
  • Further refinement is needed to balance sensitivity and specificity, especially considering sex differences.

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