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Two new tenvermectins from a genetically engineered strain Streptomyces avermitilis MHJ1011
Xu Wan1, Shao-Yong Zhang1, Hui Zhang2
1a Provincial Joint Engineering Laboratory of Biopesticide Preparation , School of Forestry & Biotechnology, Zhejiang Agricultural and Forestry University , Lin'An 311300 , China.
Abstract:
Two new tenvermectins, tenvermectins C (1) and D (2), were isolated from Streptomyces avermitilis MHJ1011. Their structures were determined by extensive spectroscopic analysis and by comparison with a related known compound, tenvermectin A. Compounds 1 and 2 exhibited potent nematocidal and acaricidal activities against Bursaphelenchus xylophilus and Tetranychus cinnabarinus.
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