Drug nanocrystals: A way toward scale-up

Area of Science:

• Pharmaceutical Sciences
• Materials Science

Background:

• Drug nanocrystals are advanced drug delivery platforms with significant industry and academic investment.
• Research is transitioning from laboratory-scale optimization to scale-up focused studies in nanocrystal technology.

Purpose of the Study:

• To review exemplary research in drug nanocrystal technology with a focus on scalability.
• To provide insights and facilitate future scale-up attempts by analyzing case studies.

Main Methods:

• Literature review of progressing research studies in drug nanocrystal technology.
• Analysis of case studies focusing on scalability or future scope for upscaling.

Main Results:

• Identified a trend towards scale-up objectives in current drug nanocrystal research.
• Highlighted the importance of analyzing existing scale-up focused studies.

Conclusions:

• Reviewing scale-up oriented research can provide valuable knowledge for future nanocrystal production.
• This analysis aims to smoothen the path for industrial-scale drug nanocrystal development.