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Cardiac catheterization is an invasive diagnostic technique used to identify and evaluate structural and functional diseases of the heart and major blood vessels. This technique diagnoses congenital heart disease, coronary artery disease, valvular heart disease, and coronary spasms and assesses ventricular function. It helps guide treatment decisions, including the need for revascularization procedures like percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG) and...
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Related Experiment Video

Updated: Mar 19, 2026

Impact of High-intensity Interval Exercise and Moderate-Intensity Continuous Exercise on the Cardiac Troponin T Level at an Early Stage of Training
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Perioperative Troponin Screening.

Daniel I Sessler1, P J Devereaux

  • 1From the *Department of Outcomes Research, Anesthesiology Institute, Cleveland Clinic, Cleveland, Ohio; and †Population Health Research Institute and Departments of ‡Clinical Epidemiology and Biostatistics and §Medicine, Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada.

Anesthesia and Analgesia
|June 23, 2016
PubMed
Summary
This summary is machine-generated.

Routine troponin screening can detect silent myocardial injury after noncardiac surgery in patients 45 and older. Early detection and intervention significantly reduce mortality risk, making screening essential for this population.

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Area of Science:

  • Cardiology
  • Perioperative Medicine
  • Geriatric Surgery

Background:

  • Myocardial injury is a leading cause of mortality within 30 days post-noncardiac surgery.
  • A significant majority (65%) of perioperative myocardial infarctions are clinically silent, often missed without routine troponin screening.
  • Asymptomatic troponin elevation carries a similar mortality risk to symptomatic elevation.

Purpose of the Study:

  • To evaluate the necessity and impact of troponin screening for detecting myocardial injury in patients undergoing noncardiac surgery.
  • To highlight the high mortality associated with postoperative troponin elevation and the benefits of early detection.

Main Methods:

  • Analysis of perioperative myocardial infarction incidence and outcomes in noncardiac surgery patients.
  • Assessment of the clinical presentation, including silent events, of myocardial injury.
  • Calculation of the number needed to screen (NNS) to detect myocardial injury in specific patient demographics.

Main Results:

  • Postoperative troponin elevation is associated with a 10% 30-day mortality, a five-fold increase in risk.
  • The number necessary to screen to detect otherwise missed myocardial injury in surgical inpatients aged 45 and older is approximately 15.
  • Routine troponin screening is deemed appropriate for most surgical inpatients aged 45 and above.

Conclusions:

  • Troponin screening is a valuable tool for identifying silent myocardial injury in the perioperative setting.
  • Early detection enables timely interventions, potentially improving outcomes and reducing mortality.
  • Screening surgical patients aged 45 and older for myocardial injury is cost-effective and clinically indicated.