[Functional morphology of the burn wound in the process of reparative regeneration]

The complex investigation of the biopsy specimens of burn wounds in dynamics of their healing in 15 male patients with IIIA-IIIB-IV degree burns was carried out. The high intensity of biosynthetic processes in the cells, which provides epidermization of the wound surface, fibrillogenesis and phagocytosis at the first 14 days of the disease, was noted. By day 21 after burn trauma, the normalization of tissue-vascular permeability and differentiation of the connective tissue were not completed. The content of RNA, different components of proteoglycans and glycogen in the skin structures has a phasic character, and reflects the course and prognosis of the processes of healing.