Related Experiment Video

Updated: Mar 19, 2026

Cardiac Magnetic Resonance for the Evaluation of Suspected Cardiac Thrombus: Conventional and Emerging Techniques
06:29

Cardiac Magnetic Resonance for the Evaluation of Suspected Cardiac Thrombus: Conventional and Emerging Techniques

Published on: June 11, 2019

11.3K

CASTLEMAN'S DISEASE PRESENTING AS A TUMOROUS PARACARDIAC FORMATION

Ivica Vuković, Toni Brešković, Darko Duplancić

    Acta Clinica Croatica
    |June 24, 2016
    PubMed

    Insights

    Castleman's disease, a rare benign lymphoproliferative disorder, can present as a paracardiac mass. Surgical excision and histopathologic analysis are crucial for diagnosis and optimal treatment of this rare condition.

    Area of Science:

    • Oncology
    • Pathology
    • Radiology

    Background:

    • Castleman's disease is a rare benign lymphoproliferative disorder.
    • It presents clinically as unicentric or multicentric disease.
    • Unicentric Castleman's disease is often discovered incidentally or due to compressive symptoms.

    Observation:

    • This report details a rare case of unicentric Castleman's disease located in the paracardiac region.
    • The patient was a previously healthy 24-year-old woman.
    • The tumor's specific location and radiological features presented a diagnostic challenge.

    Findings:

    • The paracardiac mass was confirmed as unicentric Castleman's disease post-excision.
    • Histopathologic analysis is essential for definitive diagnosis.
    • Complete surgical excision is the recommended therapeutic strategy.

    Implications:

    • This case highlights the importance of considering Castleman's disease in the differential diagnosis of paracardiac masses.
    • Rare localizations of Castleman's disease can mimic other pathologies.
    • Accurate diagnosis through histopathology following surgical resection is key for effective management.

    More Related Videos

    Isolation and Characterization of Cardiac Mesenchymal Stromal Cells from Endomyocardial Bioptic Samples of Arrhythmogenic Cardiomyopathy Patients09:16

    Isolation and Characterization of Cardiac Mesenchymal Stromal Cells from Endomyocardial Bioptic Samples of Arrhythmogenic Cardiomyopathy Patients

    Published on: February 28, 2018

    8.1K
    Cox-Maze IV Procedure Concomitant with Valvular Surgery In Situs Inversus Dextrocardia: A Single-Center Experience in China08:42

    Cox-Maze IV Procedure Concomitant with Valvular Surgery In Situs Inversus Dextrocardia: A Single-Center Experience in China

    Published on: February 11, 2022

    4.5K

    Related Concept Videos

    Cardiomyopathy III: Hypertrophic Cardiomyopathy01:29

    Cardiomyopathy III: Hypertrophic Cardiomyopathy

    Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
    636
    Cardiomyopathy II: Dilated Cardiomyopathy01:30

    Cardiomyopathy II: Dilated Cardiomyopathy

    Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...
    725
    Cardiomyopathy I: Introduction and Classification01:25

    Cardiomyopathy I: Introduction and Classification

    Cardiomyopathy, or CMP, is a group of diseases affecting the myocardial structure, impairing its ability to pump blood effectively. This condition can lead to arrhythmias, heart failure, or sudden cardiac death.Cardiomyopathies are classified into primary and secondary categories:Primary Cardiomyopathy refers to conditions involving only the heart muscle that are often idiopathic (of unknown cause) or genetic. They primarily affect the myocardium without the involvement of other systemic...
    753
    Cardiomyopathy IV: Restrictive Cardiomyopathy01:29

    Cardiomyopathy IV: Restrictive Cardiomyopathy

    Restrictive cardiomyopathy (RCM) is a rare heart muscle disease characterized by impaired ventricular filling due to stiffened ventricular walls, leading to significant diastolic dysfunction.EtiologyRestrictive cardiomyopathy can arise from both inherited and acquired diseases, many of which are systemic. It is categorized into four main types: infiltrative, storage, non-infiltrative, and endomyocardial diseases.Infiltrative diseases, such as amyloidosis, lead to RCM by depositing amyloid...
    732
    Pericarditis II: Clinical Features and Diagnostic Tests01:19

    Pericarditis II: Clinical Features and Diagnostic Tests

    Pericarditis is distinguished by inflammation of the pericardium, the fibrous sac that encases the heart. It can be acute, lasting less than six weeks, or chronic, persisting for over three months. Understanding its clinical manifestations and diagnostic findings is crucial for timely and effective management.Clinical ManifestationsWhile pericarditis can be asymptomatic, it usually presents with characteristic symptoms such as:Chest Pain: The most characteristic symptom of pericarditis is chest...
    502
    Mitral Stenosis II: Clinical features and Diagnostic Tests01:23

    Mitral Stenosis II: Clinical features and Diagnostic Tests

    Mitral stenosis is a heart condition in which the mitral valve, which allows blood to flow from the left atrium to the left ventricle, becomes narrowed or stenotic. This narrowing hinders blood flow and leads to clinical symptoms requiring specific medical evaluations and management strategies. The following overview outlines the clinical symptoms, assessments, diagnostic findings, prevention methods, and treatments for mitral stenosis.Clinical ManifestationsDyspnea (shortness of breath): This...
    393