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Achilles Tendon in Diabetes.

Lucy Partridge1, Satyan Rajbhandari2

  • 1Manchester Medical School, University of Manchester. United Kingdom.

Current Diabetes Reviews
|June 24, 2016
PubMed
Summary

Diabetes can cause Achilles tendon degeneration, but research on this link and effective treatments is limited. More studies are needed to understand and manage this complication in diabetic patients.

Keywords:
AGEAchilles tendonAchilles tendon rupturediabetic cheiroarthropathydiabetic tendinopathysport

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Area of Science:

  • Biomedical Science
  • Metabolic Disorders
  • Orthopedic Research

Background:

  • Diabetes mellitus is a prevalent metabolic disorder marked by persistent hyperglycemia.
  • Chronic hyperglycemia impacts various tissues, including the Achilles tendon, a major tendon.
  • Existing research on hyperglycemia's effects on tendons is limited, with rat models suggesting degeneration, exacerbated by neuropathy.

Purpose of the Study:

  • To systematically review the current literature on the effects of hyperglycemia on the Achilles tendon.
  • To identify gaps in epidemiological data regarding Achilles tendon rupture in diabetic individuals.
  • To explore the current knowledge on optimal treatments for Achilles tendon issues in diabetes.

Main Methods:

  • Systematic literature analysis.
  • Review of existing studies on hyperglycemia and tendon degeneration.
  • Assessment of current treatment strategies for Achilles tendon conditions in diabetes.

Main Results:

  • Limited scientific literature exists on the specific effects of hyperglycemia on the Achilles tendon.
  • Evidence from animal models indicates chronic degeneration, worsened by neuropathy and deformity.
  • There is a lack of epidemiological data on Achilles tendon rupture in diabetes patients.

Conclusions:

  • The current literature on hyperglycemia and Achilles tendon pathology is sparse.
  • Further research is required to understand the epidemiology and treatment of Achilles tendon issues in diabetes.
  • This review highlights the need for future studies in this under-researched area.