Permanent His-Bundle Pacing: Case Studies

Pugazhendhi Vijayaraman1, Gopi Dandamudi2

  • 1Division of Cardiac Electrophysiology, Geisinger Heart Institute, Wilkes-Barre, Pennsylvania.

Insights

His bundle pacing (HBP) offers a physiological alternative to traditional pacing methods. Case studies highlight HBP

Area of Science:

  • Cardiology
  • Electrophysiology
  • Medical Device Technology

Background:

  • Right ventricular pacing (RVP) is the standard pacing method.
  • RVP can lead to ventricular dyssynchrony and heart failure.
  • Physiological pacing aims to restore normal cardiac activation sequence.

Observation:

  • His bundle pacing (HBP) targets the His-Purkinje system for near-natural ventricular depolarization.
  • HBP is a viable alternative to RVP in select patient populations.
  • Challenges exist in HBP implantation and optimization.

Findings:

  • HBP demonstrates feasibility in patients with normal conduction and specific AV block types.
  • Successful HBP requires precise lead placement within the His bundle.
  • Case studies reveal potential complications and troubleshooting strategies for HBP.

Implications:

  • HBP may improve long-term cardiac function and reduce heart failure risk compared to RVP.
  • Further research is needed to define optimal patient selection criteria for HBP.
  • HBP represents a significant advancement in cardiac pacing therapy.

Related Concept Videos

Pulse rhythm01:30

Pulse rhythm

Pulse rhythm refers to the pattern of pulsations within specific intervals, offering valuable insights into the regularity or irregularity of the heart's beats as observed through the pattern of pulsation within specific intervals. A regular pulse exhibits a consistent heart rate with uniform waveforms and pulsation force, variations of which can be classified as normal, weak, or bounding.
Conversely, an irregular pulse pattern is termed dysrhythmia, stemming from disruptions in cardiac...
1.6K
Dysrhythmias IV: Characteristics of Bradyarrhythmias01:18

Dysrhythmias IV: Characteristics of Bradyarrhythmias

Bradyarrhythmias are cardiac rhythm disorders characterized by a slower-than-normal heart rate, typically defined as fewer than 60 beats per minute. Some of which are discussed here:Sinus BradycardiaSinus bradycardia presents a heart rate lower than 60 beats per minute, with a regular rhythm originating from the SA node. The ECG typically shows normal P waves preceding each QRS complex, a normal PR interval (0.12 to 0.20 seconds), and a normal QRS duration (0.06 to 0.10 seconds).First-Degree AV...
777
Cardiomyopathy III: Hypertrophic Cardiomyopathy01:29

Cardiomyopathy III: Hypertrophic Cardiomyopathy

Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
636
Cardiomyopathy II: Dilated Cardiomyopathy01:30

Cardiomyopathy II: Dilated Cardiomyopathy

Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...
725
Dysrhythmias V: Evaluating Dysrhythmias01:30

Dysrhythmias V: Evaluating Dysrhythmias

Dysrhythmias, also known as arrhythmias, are disturbances in the heart's rhythm that range from benign to life-threatening. A thorough evaluation is crucial for appropriate management and involves a comprehensive medical history, physical examination, and various diagnostic tests.Medical HistorySymptoms: Collect detailed information on palpitations, dizziness, syncope, chest pain, and fatigue. Note their onset, frequency, and triggers.Previous Cardiac Issues: Document any history of heart...
462