The Influence of Aggressive Parenteral Nutrition to Preterm and Very Low Birth Weight Infants

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Ming-Yi Liu1, Yi-Yin Chen1, Shu-Hui Hu2

  • 1Tainan Sin-Lau Hospital, Tainan, Taiwan.

Global Pediatric Health
|June 24, 2016
PubMed

Insights

Aggressive early nutrition for preterm infants, starting amino acids on day one, significantly speeds weight gain and reduces hospital stays. This approach improves nutrient delivery and tolerance, benefiting very low birth weight infants.

Area of Science:

  • Neonatalogy
  • Pediatric Nutrition
  • Intensive Care Medicine

Background:

  • Optimal nutrient delivery is crucial for preterm infant growth.
  • Interruption in nutrient supply can impede weight gain in appropriate-for-gestational-age preterm infants.

Purpose of the Study:

  • To compare the effects of conventional versus aggressive early nutrition on preterm infant growth and outcomes.
  • To evaluate the impact of early amino acid administration on weight gain and neonatal intensive care unit (NICU) length of stay.

Main Methods:

  • A study involving 28 very low birth weight infants.
  • Comparison between a conventional support (CVS) group receiving amino acids on day three and an aggressive support (AGS) group receiving amino acids on day one.
  • Both groups received 2 g/kg/day of amino acids.

Main Results:

  • Infants in the AGS group reached 2000 g significantly faster than those in the CVS group.
  • The AGS group demonstrated improved tolerance to enteral nutrition.
  • Aggressive early nutrition led to shortened neonatal intensive care unit (NICU) stays.

Conclusions:

  • Early administration of amino acids (aggressive nutrition) promotes faster weight gain in preterm infants.
  • Aggressive early nutrition enhances enteral feeding tolerance and reduces NICU duration.
  • This nutritional strategy is beneficial for very low birth weight infants requiring intensive care.

Keywords:
parenteral nutritionpostnatal growthvery low birth weight infant

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