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Related Concept Videos

Confocal Fluorescence Microscopy01:16

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Confocal microscopy is an advanced microscopic technique. The prime advantage of the confocal microscope over other microscopy techniques is its ability to block the out-of-focus light from the illuminated samples using pinholes. It is widely used with fluorescence optics to obtain high-resolution, sharp contrast images. Unlike optical microscopes, confocal microscopes use a focused beam of light laser to scan the entire sample surface at different z-planes. These microscopes are, therefore,...
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An In Vitro Approach to Photodynamic Therapy
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Photodynamic Therapy: A Clinical Consensus Guide.

David M Ozog1, Ali M Rkein, Sabrina G Fabi

  • 1*Department of Dermatology, Henry Ford Hospital, Detroit, Michigan; †English Dermatology, Gilbert, Arizona; ‡Cosmetic Laser Dermatology, San Diego, California; §University of California, San Diego, California; ¶Gold Skin Care Center, Nashville, Tennessee; ‖Cosmetic Laser Dermatology, San Diego, California; #Department of Dermatology, University of California, San Diego, California; **Cranley Clinic, London, United Kingdom; ††Dermatology Associates, Maui, Hawaii; ‡‡Dermatology, Laser, and Vein Specialists of the Carolinas, Charlotte, North Carolina; §§Wake Forest School of Medicine, Winston Salem, North Carolina.

Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [Et Al.]
|June 24, 2016
PubMed
Summary
This summary is machine-generated.

Photodynamic therapy (PDT) is an effective treatment for various skin conditions, including pre-cancerous lesions and acne. New laser-mediated protocols enhance PDT outcomes for multiple indications, offering safe and effective therapeutic options.

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Area of Science:

  • Dermatologic Surgery
  • Photodynamic Therapy

Background:

  • The American Society of Dermatologic Surgery (ASDS) periodically develops consensus documents for its members.
  • Advances in photodynamic therapy (PDT) have led to its established use in various skin conditions.

Purpose of the Study:

  • To develop evidence-based recommendations for the clinical applications of PDT.
  • An expert panel reviewed the literature and discussed findings to reach a consensus.

Main Methods:

  • A consensus document was created discussing PDT, including photosensitizers, light sources, mechanism of action, indications, outcomes, and adverse event management.
  • Literature review and expert panel discussions informed the recommendations.

Main Results:

  • Photodynamic therapy (PDT) demonstrates high efficacy for pre-cancerous lesions, superficial nonmelanoma skin cancers, and inflammatory acne vulgaris.
  • Novel protocols, such as laser-mediated PDT, significantly improve treatment results for several indications.

Conclusions:

  • The ASDS consensus document provides valuable guidance for members on the safe and effective application of PDT.
  • This document aids in educating dermatologic surgeons on utilizing PDT for diverse clinical indications.