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297
Evidence-based consensus on the clinical application of photobiomodulation
Jalal Maghfour1, Jessica Mineroff2, David M Ozog3
1Department of Dermatology, Henry Ford Health, Detroit, Michigan.
Journal of the American Academy of Dermatology
|April 19, 2025
Summary
Photobiomodulation (PBM) is a safe and effective treatment for various conditions, including wound healing and hair loss. This consensus guideline provides evidence-based recommendations for its clinical use.
Area of Science:
- Medical science
- Biotechnology
Background:
- Lack of evidence-based consensus hinders clinical photobiomodulation (PBM) application.
- Need for standardized guidelines for PBM therapy.
Purpose of the Study:
- Establish a consensus on the safe and effective use of PBM.
- Develop evidence-based clinical practice guidelines for PBM.
Main Methods:
- Systematic literature review of Embase and MEDLINE databases.
- Convening an international multidisciplinary expert panel.
- Refining recommendations through Delphi surveys and consensus meetings.
Main Results:
- Photobiomodulation (PBM) is confirmed as a safe treatment for adult patients.
- Red light PBM does not induce DNA damage.
- PBM demonstrates efficacy in treating peripheral neuropathy, androgenic alopecia, wound ulcers, decubitus ulcers, diabetic foot ulcer pain, and radiation dermatitis.
Conclusions:
- An evidence-based clinical practice guideline for PBM has been established.
- The guideline covers both medical and aesthetic applications of PBM.
- Further research is recommended to advance understanding of this non-invasive technique.
