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Human absorbed dose estimation for a new (175)Yb-phosphonate based on rats data: Comparison with similar bone pain
Mahdokht Vaez-Tehrani1, Samaneh Zolghadri2, Hassan Yousefnia2
1Energy Engineering and Department of Physics, Amir Kabir University of Technology, Tehran, Iran.
Abstract:
In this work, the absorbed dose to human organs for (175)Yb-BPAMD was evaluated based on the biodistribution studies in rats. The results showed that the bone surface would receive the highest absorbed dose after injection of (175)Yb-BPAMD with 13.32mGy/MBq, while the other organs receive insignificant absorbed dose. Also, the comparison of (175)Yb-BPAMD with other therapeutic phosphonate complexes demonstrated noticeable characteristics for this new agent. Generally, based on the obtained results, (175)Yb-BPAMD can be considered as a promising agent for bone pain palliative therapy in near future.

