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Prospective study comparing hydrogel with PMMA lens implants.

P Percival1

  • 1Scarborough Hospital Department of Ophthalmology, UK.

Ophthalmic Surgery
|April 1, 1989
PubMed
Summary
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Poly 2-hydroxyethylmethacrylate (P-HEMA) lenses showed superior visual acuity compared to polymethylmethacrylate (PMMA) lenses six months post-surgery. While PMMA lenses offered greater adaptability, P-HEMA lenses resulted in better visual outcomes in this study.

Area of Science:

  • Ophthalmology
  • Biomaterials Science

Background:

  • Intraocular lens (IOL) technology has advanced significantly.
  • Comparing different IOL materials is crucial for optimizing surgical outcomes.

Purpose of the Study:

  • To compare the clinical performance of one-piece polymethylmethacrylate (PMMA) and poly 2-hydroxyethylmethacrylate (P-HEMA) intraocular lenses.
  • To assess visual acuity and lens centration in uncomplicated eyes after cataract surgery.

Main Methods:

  • A prospective study involving 250 eyes (125 PMMA, 125 P-HEMA) matched for age and sex.
  • Evaluation of visual acuity and lens centration at six months post-surgery.

Main Results:

  • P-HEMA lenses achieved 20/15 visual acuity in 42% of eyes, compared to 29% for PMMA lenses (p=0.02).

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  • Asymptomatic subclinical decentration was more frequent with PMMA lenses (p<0.001).
  • Two cases of major decentration were observed with P-HEMA lenses.

    • Conclusions:

    • P-HEMA intraocular lenses demonstrate a potential for better visual acuity outcomes compared to PMMA lenses.
    • PMMA lenses, particularly looped designs, may offer greater adaptability in diverse surgical scenarios.
    • Further research into IOL material properties and long-term outcomes is warranted.