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Updated: Mar 19, 2026

Lipid Droplet Isolation for Quantitative Mass Spectrometry Analysis
Published on: April 17, 2017
Small Drops Get Fat: Unexpected Fatty Acid in Cytoplasmic Lipid Droplets
1Department of Urology, Medical University of Innsbruck, 6020 Innsbruck, Austria.
Abstract:
In a model of transcellular lipid biosynthesis, Guijas et al. (2016), in this issue of Cell Chemical Biology, demonstrate that lipid droplet-containing "foamy" monocytes unexpectedly accumulate 16:1n9-palmitoleic acid, which has anti-inflammatory function in vitro and in vivo. This uncommon positional isomer of 16:1n7-palmitoleic acid represents a candidate biomarker for early cardiovascular disease detection.
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