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How to produce high specific activity tin-117m using alpha particle beam
C Duchemin1, M Essayan1, A Guertin1
1SUBATECH, Ecole des Mines de Nantes, Université de Nantes, CNRS/IN2P3, 44307 Nantes, France.
Summary
High specific activity tin-117m, crucial for medical imaging and therapy, can be produced using alpha particles and a cadmium target. Experiments optimized irradiation conditions for producing this radionuclide with desired activity levels.
Area of Science:
- Nuclear Physics
- Radiochemistry
- Medical Isotope Production
Background:
- Tin-117m is a medically significant radionuclide due to its decay properties, emitting gamma rays for diagnosis and electrons for therapy.
- High specific activity of tin-117m is essential for effective medical applications.
- Production of tin-117m typically involves high-energy particle beams and specific target materials.
Purpose of the Study:
- To measure the excitation function of the natCd(α,x)Sn-117m reaction.
- To determine the production cross-section of Cd-116(α,3n)Sn-117m.
- To calculate production yield and specific activity to optimize tin-117m production.
Main Methods:
- Experiments were conducted at the ARRONAX cyclotron using a 67.4 MeV alpha particle beam.
- Natural cadmium was used as the target material.
- Excitation function and contaminant production were measured.
Main Results:
- The excitation function for the natCd(α,x)Sn-117m reaction was experimentally determined.
- The production cross-section for Cd-116(α,3n)Sn-117m was deduced.
- Production yield and specific activity were calculated as a function of alpha particle energy.
Conclusions:
- The study provides crucial data for optimizing the production of tin-117m.
- Irradiation conditions can be fine-tuned to achieve the required specific activity for medical uses.
- This research aids in the efficient production of tin-117m using alpha particles and a cadmium target.