Related Experiment Video
Updated: Mar 18, 2026

09:06
Live-3D-Cell Immunocytochemistry Assays of Pediatric Diffuse Midline Glioma
Published on: November 11, 2021
3.1K
[Frontal fibrosing alopecia: Report on three pediatric cases]
H Atarguine1, O Hocar1, A Hamdaoui2
1Service de dermatologie, hôpital Errazi, CHU Mohamed VI, faculté de médecine et pharmacie, université Cadi Ayyad, 53, rue Assif-D., 40000 Marrakech, Maroc.
Summary
Frontal fibrosing alopecia, a scarring condition, is reported in three pediatric cases, including twins. This expands understanding of the condition beyond postmenopausal women.
Area of Science:
- Dermatology
- Pediatric Dermatology
- Trichology
Background:
- Frontal fibrosing alopecia (FFA) is a scarring alopecia typically affecting postmenopausal women.
- FFA is a variant of lichen planopilaris.
- This study presents the first reported pediatric cases of FFA.
Observation:
- Three pediatric cases of FFA are detailed, including 14-year-old female twins and a 7-year-old girl.
- Onset in the twin sisters began at age 5, presenting with frontotemporal alopecia and micropapules.
- The second case involved a frontotemporal band of alopecia and eyebrow hair loss.
Findings:
- Histological examination revealed hair follicle depletion, dermal fibrosis, and perivascular infiltrate consistent with lichen planopilaris.
- Intralesional betamethasone was administered to the twins.
- The 7-year-old patient received oral steroids with a favorable outcome.
Implications:
- These cases highlight that frontal fibrosing alopecia can occur in children.
- The findings broaden the known demographic for FFA, previously considered postmenopausal.
- Early diagnosis and treatment in pediatric FFA may be crucial for managing this scarring alopecia.

