Related Experiment Video
Updated: Mar 18, 2026

Pre-Chiasmatic, Single Injection of Autologous Blood to Induce Experimental Subarachnoid Hemorrhage in a Rat Model
Published on: June 18, 2021
[Chronic subdural haematomas in very elderly patients]
Cristina Castro-Rodríguez1, Paula Román-Pena2, Eduardo Arán-Echabe2
1Departamento de Cirugía, Universidad de Santiago de Compostela, Santiago de Compostela, España.
Insights
Chronic subdural hematoma (CSDH) is common in the elderly. Preoperative neurological status significantly impacts recurrence and mortality in patients over 85 undergoing CSDH treatment.
Area of Science:
- Neurosurgery
- Geriatric Medicine
- Neurology
Background:
- Chronic subdural hematoma (CSDH) is a frequent neurosurgical condition, particularly in elderly populations.
- This study focuses on analyzing CSDH in patients aged 85 and above.
Purpose of the Study:
- To analyze demographic, clinical, and radiological findings in elderly patients (over 85 years) with CSDH.
- To evaluate surgical outcomes, including complications, recurrence, and mortality, in this specific age group.
Main Methods:
- Retrospective review of 200 patients over 85 years with CSDH treated between April 1986 and November 2015.
- Data collected included patient characteristics, comorbidities, risk factors, imaging details, and surgical outcomes.
- Analysis of factors such as gender, clinical grade, antithrombotic therapy, and hematoma characteristics in relation to mortality and recurrence.
Main Results:
- The study included 200 patients (mean age 88.5 years), with a 1:1.1 male:female ratio.
- 57% reported a history of injury; 35.5% were on anti-platelet or anticoagulant therapy.
- Behavioral disturbance was the most common symptom (41%). Postoperative complications occurred in 29% of cases, with 29% recurrence rate.
- Preoperative Markwalder grade significantly correlated with recurrence and mortality (P<.0001).
Conclusions:
- CSDH is highly prevalent in the very elderly population.
- Behavioral disturbances and neurological deficits are common initial symptoms.
- Preoperative neurological status is a critical predictor of recurrence and mortality in elderly CSDH patients.
Introduction:
Chronic subdural haematoma (CSDH) is one of the most common neurosurgical conditions and is especially prevalent among elderly individuals. The objective of this study was to analyse the demographic, clinical and radiological findings, and surgical outcomes in a series of chronic subdural haematoma in patients older than 85 years.
Patients And Methods:
A review was carried out on all patients over 85 years with CSDH treated in our neurosurgical service from April 1986 to November 2015. A record was made of the baseline patient characteristics (age, sex, comorbidities, known risk factors, imaging characteristics, and number of burr-holes) and surgical outcomes (complications, especially recurrences and mortality). An analysis was carried out on the special characteristics of these patients, as well as the relationships between gender, clinical grade, anti-platelet or anticoagulant therapy, internal architecture of the haematoma, and midline shift, with mortality and recurrence of the haematoma.
Results:
A total of 200 patients were included, with a mean age of 88.5 (range 85-104) years, and the male: female sex ratio was 1:1.1. History of injury was reported in 114 (57%) cases. Anti-platelet or anticoagulant therapy was being used by 71 (35.5%) patients. On admission, 114 patients (57%) were in satisfactory condition (Markwalder grades 0-2). The main symptom was behavioural disturbance in 82 (41%) cases. CSDH was left-sided in 89 (44.5%) patients, right-sided in 78 (39%) cases (39%), and bilateral in the remaining 33 (16.5%) cases). Postoperative complications were observed in 59 cases (29 recurrences). Preoperative Markwalder grade correlated significantly with recurrence rate and mortality (P<.0001).
Conclusions:
CSDH was a very common disease in very elderly patients. Behavioural disturbance and neurological deficits are the most common first symptom. Preoperative neurological status at admission is the most important factor in recurrences and mortality.
More Related Videos
08:29Symmetric Bihemispheric Postmortem Brain Cutting to Study Healthy and Pathological Brain Conditions in Humans
Published on: December 18, 2016
11:58Minimally Invasive Thumb-sized Pterional Craniotomy for Surgical Clip Ligation of Unruptured Anterior Circulation Aneurysms
Published on: August 11, 2015
Related Concept Videos
Drug Dosing: Geriatric Patients
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion
Pharmacodynamics in Geriatric Patients: Effects of Age