Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy01:30

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy

1.0K
Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
1.0K
Phases of Wound Repair01:28

Phases of Wound Repair

9.3K
Following injury, the integrity of the injured tissues must be reestablished. For example, in skin tissue, wound repair involves coordination among resident skin cells, blood mononuclear cells, extracellular matrix, growth factors, and cytokines to complete the healing cascade.
Formation of Blood Clot
In case of deep injuries, trauma to blood vessels results in blood loss. In the meantime, phospholipids released from the ruptured endothelial cellular membrane are converted into arachidonic...
9.3K
Overview of Regeneration and Repair01:19

Overview of Regeneration and Repair

5.7K
Regeneration and repair processes are critical in healing damages caused by injury, disease, and aging. In regeneration, the damaged tissue is entirely replaced with new growth that restores the original architecture and function. In contrast, tissue repair usually results in a fixed tissue architecture involving scar formation. Scars generally do not reestablish tissue function and may also exhibit structural abnormalities at the injury site.
Regeneration
All animals have varying degrees of...
5.7K
Role Of Notch Signalling In Intestinal Stem Cell Renewal01:12

Role Of Notch Signalling In Intestinal Stem Cell Renewal

2.6K
Notch signaling was first discovered in Drosophila melanogaster, where it is involved in cell lineage differentiation. Notch signaling regulates the maintenance and differentiation of intestinal stem cells or ISCs by controlling the expression of atonal homolog 1 or Atoh1. Atoh1 directs cells to differentiate into secretory cells.
Direct cell-to-cell contact is needed for the activation of Notch signaling. The signal is initiated when a notch ligand binds to a receptor on an adjacent cell, also...
2.6K
Renewal of Intestinal Stem Cells01:23

Renewal of Intestinal Stem Cells

3.5K
The intestinal epithelial lining rapidly renews every 4 to 5 days. The renewal is facilitated by intestinal stem cells (ISCs) located at the base of the crypt– a gland located at the bottom of each villus. ISCs divide asymmetrically to form new stem cells and progenitor daughter cells. The daughter cells are called transit-amplifying (TA) cells which move upwards along the crypt and either differentiate into absorptive cells– the enterocytes or secretory cells– including the...
3.5K
Inflammatory Response II: Inflammatory Exudate and Tissue Repair01:24

Inflammatory Response II: Inflammatory Exudate and Tissue Repair

8.8K
The immune system's inflammatory response destroys the invading pathogen, permitting the tissue to heal. The changes during the cellular and vascular stages allow exudate formation at the site of inflammation. The inflammatory exudate released from the wound has high protein content and a specific gravity above 1.020.
The typical wound exudate is odorless, transparent, straw-colored, thin, and watery. Exudate, however, can differ depending on the state of wound healing. Likewise, the...
8.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Blunted anticipation, but not consummation, of food rewards in depression.

Cell reports. Medicine·2026
Same author

Effects of regular consumption of a β-glucan-rich oyster mushroom powder on cholesterol metabolism in adults with moderately elevated LDL-cholesterol concentrations: a double-blind randomized controlled trial.

Nutrition & metabolism·2026
Same author

Protein intake and cardiovascular diseases: an umbrella review of systematic reviews for the evidence-based guideline on protein intake of the German Nutrition Society.

European journal of nutrition·2025
Same author

GLP-1 Responses to a Single Meal Fortified With Oyster Mushroom Powder in Adults With Impaired Glucose Tolerance Depend on the Gut Microbiota Composition Before the Meal.

Molecular nutrition & food research·2025
Same author

Altered food liking in depression is driven by macronutrient composition.

Psychological medicine·2025
Same author

Cardiometabolic Impact of Encapsulated Cocoa Powder and Pure Cocoa Ingredients Supplementation: A Comparative Placebo-Controlled RCT in Adults.

Molecular nutrition & food research·2025

Related Experiment Video

Updated: Mar 18, 2026

Assessment of Acute Wound Healing using the Dorsal Subcutaneous Polyvinyl Alcohol Sponge Implantation and Excisional Tail Skin Wound Models.
09:06

Assessment of Acute Wound Healing using the Dorsal Subcutaneous Polyvinyl Alcohol Sponge Implantation and Excisional Tail Skin Wound Models.

Published on: March 25, 2020

10.0K

Can specific nutrients stimulate bowel wound healing?

Sabine Ellinger1

  • 1Faculty of Food, Nutrition and Hospitality Sciences, Hochschule Niederrhein, University of Applied Sciences, Mönchengladbach, Germany.

Current Opinion in Clinical Nutrition and Metabolic Care
|June 28, 2016
PubMed
Summary
This summary is machine-generated.

Nutrients like glutamine and arginine are vital for bowel wound healing. However, only specific enteral formulas show proven benefits for patients undergoing colon surgery, requiring more research on individual nutrient efficacy.

More Related Videos

Chessboard-like Burn Wound Healing Model of Mice Based on Digital Heating Device
04:04

Chessboard-like Burn Wound Healing Model of Mice Based on Digital Heating Device

Published on: December 27, 2024

1.8K
Analyzing Beneficial Effects of Nutritional Supplements on Intestinal Epithelial Barrier Functions During Experimental Colitis
08:58

Analyzing Beneficial Effects of Nutritional Supplements on Intestinal Epithelial Barrier Functions During Experimental Colitis

Published on: January 5, 2017

13.0K

Related Experiment Videos

Last Updated: Mar 18, 2026

Assessment of Acute Wound Healing using the Dorsal Subcutaneous Polyvinyl Alcohol Sponge Implantation and Excisional Tail Skin Wound Models.
09:06

Assessment of Acute Wound Healing using the Dorsal Subcutaneous Polyvinyl Alcohol Sponge Implantation and Excisional Tail Skin Wound Models.

Published on: March 25, 2020

10.0K
Chessboard-like Burn Wound Healing Model of Mice Based on Digital Heating Device
04:04

Chessboard-like Burn Wound Healing Model of Mice Based on Digital Heating Device

Published on: December 27, 2024

1.8K
Analyzing Beneficial Effects of Nutritional Supplements on Intestinal Epithelial Barrier Functions During Experimental Colitis
08:58

Analyzing Beneficial Effects of Nutritional Supplements on Intestinal Epithelial Barrier Functions During Experimental Colitis

Published on: January 5, 2017

13.0K

Area of Science:

  • Gastroenterology
  • Surgical Nutrition
  • Wound Healing Research

Background:

  • Bowel wound healing involves numerous nutrients, including glutamine, arginine, butyrate, omega-3 fatty acids, nucleotides, and micronutrients.
  • The precise role and clinical efficacy of individual nutrient supplementation in inflammatory bowel disease (IBD) patients remain unclear.
  • Understanding nutrient roles is crucial for optimizing post-operative recovery and managing gastrointestinal conditions.

Purpose of the Study:

  • To review key nutrients involved in bowel wound healing.
  • To evaluate the efficacy of nutrient supplementation for clinical practice recommendations.
  • To synthesize current evidence on nutritional support for intestinal repair.

Main Methods:

  • Systematic review of literature on nutrients and bowel wound healing.
  • Analysis of clinical trial data regarding nutrient supplementation efficacy.
  • Assessment of evidence for perioperative nutritional interventions.

Main Results:

  • Several nutrients (glutamine, arginine, butyrate, omega-3 fatty acids, nucleotides, micronutrients) are implicated in bowel wound healing.
  • Clinical trial evidence for individual nutrient supplementation in IBD patients is insufficient.
  • Perioperative enteral immunomodulating formulas (arginine, nucleotides, omega-3 fatty acids) show efficacy in colon surgery patients, reducing complications like infections and dehiscence.

Conclusions:

  • While various nutrients support bowel wound healing, only perioperative enteral immunomodulating formulas are currently recommended for colon surgery patients, particularly those with cancer.
  • Further randomized controlled trials are necessary to clarify the efficacy of individual nutrients in promoting intestinal wound healing.
  • Evidence-based nutritional strategies are essential for improving outcomes in gastrointestinal surgery and disease.