Left Ventricular Mechanics in Functional Ischemic Mitral Regurgitation in Acute Inferoposterior Myocardial Infarction
Zivile Valuckiene1, Justas Ovsianas1,2, Ruta Ablonskyte-Dudoniene1
1Department of Cardiology, Lithuanian University of Health Sciences, Eiveniu 2, LT-50009, Kaunas, Lithuania.
Echocardiography (Mount Kisco, N.Y.)
|June 29, 2016
Summary
Ischemic mitral regurgitation (MR) after myocardial infarction (MI) is linked to impaired left ventricular (LV) mechanics. Two-dimensional speckle tracking revealed worse radial and circumferential deformation in patients with ischemic MR.
Area of Science:
- Cardiology
- Echocardiography
- Cardiac Mechanics
Background:
- Ischemic mitral regurgitation (MR) is a known negative prognostic factor following myocardial infarction (MI).
- Functional ischemic MR during the acute phase of MI is often transient and dynamic, making it under-investigated.
Purpose of the Study:
- To evaluate left ventricular (LV) mechanics using speckle-tracking echocardiography in patients with acute inferoposterior MI and ischemic MR.
- To compare LV deformation parameters between patients with and without significant ischemic MR.
Main Methods:
- Sixty-nine patients with acute inferoposterior MI were prospectively studied within 48 hours of reperfusion therapy.
- Two-dimensional transthoracic echocardiography assessed regional myocardial function and valve status.
- Patients were categorized into no significant MR (NMR) and ischemic MR (IMR) groups; 35 healthy individuals served as controls.
Main Results:
- LV ejection fraction and longitudinal strain did not differ between MI groups but were better in healthy subjects.
- Circumferential strain parameters were significantly worse in the IMR group compared to healthy subjects and the NMR group.
- Global, basal, and mid-ventricular radial strain were significantly lower in the IMR group versus both other groups.
Conclusions:
- Acute inferoposterior MI with ischemic MR is associated with impaired radial and circumferential LV mechanics.
- 2D speckle tracking echocardiography can identify these mechanical abnormalities in ischemic MR.
More Related Videos
Related Concept Videos
01:20Mitral Regurgitation I: Introduction
885
Mitral regurgitation is characterized by the backward circulation of blood from the left ventricle to the left atrium during systole, a phase of the cardiac cycle when the heart contracts and pumps blood out of the chambers. This abnormal flow occurs primarily due to the dysfunction of the mitral valve or its supporting structures, which include the mitral leaflets, chordae tendineae, annulus, and papillary muscles.Etiology and Mechanisms:Primary Mitral Regurgitation: This type arises from...
885
01:23Mitral Regurgitation II: Clinical Features and Diagnostic Tests
729
Mitral regurgitation (MR) is a valvular heart disorder in which the mitral valve fails to close tightly, allowing blood to leak backward into the heart. Understanding the clinical manifestations, assessment, diagnostic findings, and medical management of MR is crucial to effectively managing affected patients.Clinical Manifestations of Mitral RegurgitationMitral regurgitation can be acute or chronic, each presenting differently and requiring different approaches:1. Acute Mitral...
729
01:22Mitral Stenosis I: Introduction
1.1K
Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
1.1K
01:25Mitral Regurgitation III: Medical Management
510
Mitral regurgitation (MR) is characterized by retrograde blood circulation from the left ventricle into the left atrium due to inadequate mitral valve closure. The severity of the condition, symptoms, and underlying cause determine treatment strategies.Monitoring and Pharmacological TreatmentPatients with mild to moderate MR typically do not need immediate intervention but regular monitoring to assess progression and guide treatment. Patients with mild MR should have an echocardiogram every 3-5...
510
01:28Mitral Regurgitation IV: Nursing Management
485
Mitral regurgitation (MR) is a condition where the mitral valve does not close properly, leading to the backward flow of blood from the left ventricle into the left atrium during systole. This condition can arise from various causes, including rheumatic fever, infective endocarditis, or degenerative valve disease. Effective nursing management is crucial to optimizing patient outcomes and involves comprehensive assessment and targeted interventions.Comprehensive Patient AssessmentA detailed...
485
01:27Mitral Valve Prolapse I: Introduction
855
IntroductionThe mitral valve, one of the heart's four valves, regulates blood flow. These valves have flaps that open and close to direct blood properly through the heart and body. During each heartbeat, the flaps open for blood to pass through and seal shut to prevent backflow. Specifically, the mitral valve opens to allow blood flow from the heart's upper left chamber to the lower left chamber. It then closes securely as the lower left chamber contracts to pump blood to the body, preventing...
855