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Related Concept Videos

Rheumatic Heart Disease I: Introduction01:23

Rheumatic Heart Disease I: Introduction

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Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...
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Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies01:22

Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies

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The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
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Mitral Stenosis I: Introduction01:22

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Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
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Aortic Regurgitation II: Clinical Features and Diagnostic Tests01:22

Aortic Regurgitation II: Clinical Features and Diagnostic Tests

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Aortic valve regurgitation (AR) occurs when the aortic valve fails to close properly, allowing blood to flow backward from the aorta into the left ventricle. This backflow can result in two distinct clinical presentations: acute and chronic AR, each characterized by its own set of symptoms and physical findings.Acute Aortic RegurgitationAcute AR presents with a sudden onset of severe symptoms. Patients typically experience profound dyspnea (shortness of breath), chest pain, and signs of left...
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Aortic Regurgitation III: Medical Management01:25

Aortic Regurgitation III: Medical Management

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Aortic regurgitation (AR) is when the aortic valve does not close or seal properly, leading to backward blood circulation from the aorta into the left ventricle during diastole. Common causes of AR include rheumatic heart disease, congenital valve defects, and aortic root dilation. Managing AR requires a multifaceted approach to alleviate symptoms, preserve left ventricular function, and address the underlying cause of the regurgitation. Patients with symptomatic AR or significant left...
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Mitral Regurgitation I: Introduction01:20

Mitral Regurgitation I: Introduction

885
Mitral regurgitation is characterized by the backward circulation of blood from the left ventricle to the left atrium during systole, a phase of the cardiac cycle when the heart contracts and pumps blood out of the chambers. This abnormal flow occurs primarily due to the dysfunction of the mitral valve or its supporting structures, which include the mitral leaflets, chordae tendineae, annulus, and papillary muscles.Etiology and Mechanisms:Primary Mitral Regurgitation: This type arises from...
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Related Experiment Video

Updated: Mar 18, 2026

Echocardiographic Evaluation of Atrial Communications before Transcatheter Closure
07:41

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Asymptomatic post-rheumatic giant left atrium.

Tardu Özkartal1, Felix C Tanner1, Markus Niemann1

  • 1Tardu Özkartal, Felix C Tanner, Clinic of Cardiology, University Heart Center, University Hospital Zurich, 8091 Zurich, Switzerland.

World Journal of Cardiology
|June 30, 2016
PubMed
Summary
This summary is machine-generated.

A giant left atrium, defined by a left atrial volume index exceeding 140 mL/m², was identified in an asymptomatic patient. This finding highlights the importance of left atrial volume index in diagnosing giant left atrium.

Keywords:
AtriumGiantLeftMitralPostrheumaticRegurgitationStenosisValve

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Area of Science:

  • Cardiology
  • Echocardiography
  • Cardiac Surgery

Background:

  • Mitral valve disease evaluation often involves assessing left atrial size.
  • Giant left atrium diagnosis traditionally relies on M-mode measurements, which can be less accurate.
  • Accurate assessment of left atrial size is crucial for surgical decision-making in mitral valve disease.

Observation:

  • An echocardiogram revealed moderate mitral stenosis with severe regurgitation in a 78-year-old asymptomatic woman.
  • A striking finding was a giant left atrium with a parasternal anteroposterior diameter of 79 mm.
  • The left atrial volume index was measured at 364 mL/m², significantly exceeding typical values.

Findings:

  • Existing echocardiographic definitions for giant left atrium vary and often use less precise M-mode measurements.
  • The study proposes a new, more accurate definition for giant left atrium based on left atrial volume index.
  • A proposed cut-off value of 140 mL/m² for left atrial volume index is suggested to define a giant left atrium.

Implications:

  • The proposed definition using left atrial volume index offers a standardized and more reliable method for diagnosing giant left atrium.
  • This refined definition can improve the accuracy of surgical planning and patient management for mitral valve disease.
  • Further research may validate this new criterion, enhancing echocardiographic assessment in clinical practice.