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Updated: Jun 26, 2026

MRI and PET in Mouse Models of Myocardial Infarction
Published on: December 19, 2013
[Multimodal imaging in cardiac amyloidosis and cardiac sarcoidosis]
Markus Niemann1,2,3, Tobias A Fuchs1,2
1Furtwangen University, Faculty Health Medical and Life Sciences, Villingen-Schwenningen, Germany.
Introduction:
Cardiac amyloidosis and cardiac sarcoidosis can be classified as infiltrative cardiomyopathies. Although the aetiology and underlying pathophysiology of these two conditions differ substantially, imaging techniques are becoming increasingly important for both. Only a decade ago myocardial biopsy used to be essential for establishing the diagnosis, contemporary diagnostic algorithms for both diseases now rely predominantly on non-invasive cardiac imaging, enabling not only accurate diagnosis but also guiding therapeutic decision-making. In this review, we aim to highlight the respective strengths and limitations of the available cardiac imaging modalities as they relate to these disorders. Particular emphasis will be placed on disease detection and the differential diagnosis between amyloidosis and sarcoidosis, and its value for prognostic assessment. Where appropriate, we will also discuss recent advances in multimodality imaging and how they have reshaped clinical pathways and management strategies.
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