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Rapid Intravenous Rehydration to Correct Dehydration and Resolve Vomiting in Children with Acute Gastroenteritis
Anoush Azarfar1, Yalda Ravanshad1, Aghillolah Keykhosravi1
1Mashhad University of Medical Sciences, Mashhad, Iran.
Insights
Rapid intravenous rehydration effectively resolves vomiting in children with acute gastroenteritis, reducing emergency department admissions. This approach aids in quicker recovery for pediatric patients experiencing dehydration.
Area of Science:
- Pediatric Emergency Medicine
- Gastroenterology
- Clinical Trials
Background:
- Acute gastroenteritis is a common cause of vomiting and dehydration in children.
- Oral rehydration therapy is often insufficient for moderately dehydrated children with persistent vomiting.
- Prompt intervention is crucial to prevent complications and reduce healthcare resource utilization.
Purpose of the Study:
- To assess the efficacy of rapid intravenous rehydration in resolving vomiting among children with acute gastroenteritis.
- To compare the outcomes of rapid intravenous rehydration versus standard emergency department observation for hydration.
- To determine the impact of rapid intravenous rehydration on pediatric emergency department admission rates.
Main Methods:
- A randomized controlled trial involving 150 children with acute gastroenteritis, moderate dehydration, and vomiting unresponsive to oral rehydration.
- The intervention group received 20-30 cc/kg of crystalloid solution intravenously over 2 hours.
- The control group received standard 24-hour hydration management in the emergency department.
Main Results:
- Vomiting resolved in 63 of 75 children (84%) receiving rapid intravenous rehydration, leading to their discharge.
- Among those treated with rapid IV rehydration, 12 children who could not tolerate oral fluids were admitted.
- In the control group, vomiting resolved within 4 hours for 62 patients, with no significant difference in vomiting resolution between groups.
Conclusions:
- Rapid intravenous rehydration is an effective strategy for resolving vomiting in children with moderate dehydration due to gastroenteritis.
- This intervention significantly reduces the need for emergency department admissions in pediatric patients.
- Faster resolution of vomiting through rapid IV fluids can improve patient outcomes and streamline emergency care.
Objectives:
The objective of this study is to evaluate the effect of rapid intravenous rehydration to resolve vomiting in children with acute gastroenteritis.
Methods:
This randomized control trial was conducted in the pediatric emergency department in a tertiary care center in Tabriz, North-West of Iran. The study participants' were 150 children with acute gastroenteritis and vomiting who were moderately dehydrated, had not responded to oral rehydration therapy and without any electrolyte abnormalities. 20-30 cc/kg of a crystalloid solution was given intravenously over 2 hours and the control group was admitted in the emergency department (ED) for a standard 24 hour hydration. Effectiveness of rapid intravenous rehydration in the resolution of vomiting in children with acute gastroenteritis was evaluated.
Results:
In 63 children of the intervention group (out of 75) vomiting was resolved after rapid IV rehydration and they were discharged. Among them, 12 that did not tolerate oral fluids were admitted. In the control group, 62 patients' vomiting was resolved in the first 4 hours after admission, and there was no significant difference between the two groups regarding resolution of vomiting.
Conclusions:
Rapid intravenous rehydration in children with moderate dehydration and vomiting due to gastroenteritis is effective in reducing admission rates in the ED.
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