Related Experiment Video
Updated: Mar 18, 2026

Guidelines for Elective Pediatric Fiberoptic Intubation
Published on: January 17, 2011
A Pediatric Sedation Protocol for Mechanically Ventilated Patients Requires Sustenance Beyond Implementation
Beryl F Yaghmai1, Jane L Di Gennaro, Gretchen A Irby
11Department of Critical Care Medicine, Wesley Children's Hospital, Wichita, KS. 2Department of Critical Care Medicine, Seattle Children's Hospital, Seattle, WA. 3Department of Pharmacy, Seattle Children's Hospital, Seattle, WA. 4Department of Critical Care Medicine, Joe DiMaggio Children's Hospital, Hollywood, FL.
A nursing-driven sedation protocol initially reduced sedation exposure in mechanically ventilated children. However, without ongoing quality improvement, sedation duration and mechanical ventilation days increased over time.
Area of Science:
- Pediatric Critical Care Medicine
- Nursing Quality Improvement
- Pharmacological Management
Background:
- Sedation protocols are crucial for managing mechanically ventilated patients.
- Sustained quality improvement requires continuous monitoring and education.
- Initial implementation of a sedation protocol may not guarantee long-term effectiveness.
Purpose of the Study:
- To reevaluate the long-term effect of a nursing-driven sedation protocol on medication dosing durations.
- To assess if quality improvement efforts impact sedation exposure, mechanical ventilation, and ICU length of stay.
- To determine the sustainability of a sedation protocol's effectiveness.
Main Methods:
- A quasi-experimental, uncontrolled before-after study design was employed.
- Data were collected from a 45-bed pediatric intensive care unit (PICU).
- Two cohorts of children requiring mechanical ventilation >48 hours were compared before and after protocol implementation.
Main Results:
- The postintervention cohort showed a significant increase in median sedation days (5 vs 10 days).
- Mechanical ventilation duration (5 vs 6 days) and ICU length of stay (8.5 vs 10 days) also increased.
- Patients in the postintervention group were more likely to receive sedation and remain in the ICU.
Conclusions:
- Sedation quality improvement measures deteriorated over time without continued efforts.
- Protocol implementation alone is insufficient for sustained quality improvement.
- Routine monitoring and ongoing education are essential for maintaining protocol effectiveness.
More Related Videos
Related Concept Videos
Parenteral Anesthetics: Overview
Mechanical Ventilation I: Indication and Settings
Stages of General Anesthesia
Cardiopulmonary Resuscitation II: ACLS Airway Management
Inhalational Anesthetics: Overview
Administering Oxygen by Mask
Administering oxygen by mask is a common nursing intervention that provides supplemental oxygen to patients with respiratory distress or chronic lung conditions. This procedure involves delivering oxygen at a specified rate through a face mask connected to an oxygen source.
Equipment
The equipment necessary for this procedure includes:

