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Updated: Mar 18, 2026

Bone Marrow Transplantation Platform to Investigate the Role of Dendritic Cells in Graft-versus-Host Disease
Published on: March 17, 2020
Transient acantholytic dyskeratosis (Grover's disease) after bone marrow transplantation
Penny Poh Lu Lim1, Pablo Fernandez Penas1,2, David Gottlieb2
1Skin and Cancer Foundation, Sydney, New South Wales, Australia.
Abstract:
Cutaneous eruptions in recipients of allogeneic haematopoietic stem cell transplantation (AHSCT) are frequent, and common aetiologies include graft-versus-host disease (GVHD), drug reactions, viral infections and engraftment syndrome. Transient acantholytic dermatosis or Grover's disease has been described in oncology patients and it is rarely reported after AHSCT. However, this benign and self-limiting condition should be histologically distinguished from other, more serious entities, mainly stage IV GVHD, in order to avoid inappropriate treatment with corticosteroids and intensive immunosuppression.
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