Related Experiment Video
Updated: Mar 18, 2026

Dural Stimulation and Periorbital von Frey Testing in Mice As a Preclinical Model of Headache
Published on: July 29, 2021
A Historical Recount: Discovering Menière's Disease and Its Association With Migraine Headaches
Omid Moshtaghi1, Ronald Sahyouni, Harrison W Lin
1*Division of Neurotology and Skull Base Surgery, Department of Otolaryngology-Head and Neck Surgery †Department of Biomedical Engineering, University of California, Irvine, California.
Objectives:
In evaluating the historical context of the first description of Menière's disease, its association with migraine headaches is compelling. We have outlined the events and observations of Prosper Menière, which led him to establish a link between migraine headaches and his eponymous disease.
Study Design:
Prosper Menière's original French writings were translated by our group and used to recount his observations and thoughts. Miles Atkinson's English translations were used as a reference. Additional otological texts of the era were also reviewed as it relates to Menière's disease.
Methods:
Prosper Menière wrote a series of four articles 1 year before his death. In one of these articles, he makes references to migraine headaches on several occasions. These original writings were analyzed, and the physical findings he described were interpreted based on their relation to migraine headaches.
Results:
The passages in his published articles provide historical insight into Menière's observations. His writings describe in detail symptoms of migraine headaches uniquely evident in his patient population. Through his observations, he recognized that in addition to exhibiting symptoms of tinnitus, hearing loss and vertigo his patients also suffered from migraine headaches.
Conclusions:
Although his colleagues discounted Menière's theory concerning migraine headaches, he continued to make deductive inferences and publish his findings, leading to the association of migraine headaches and Menière's disease. Today, this association continues to be debated, adding to Prosper Menière's legacy.
Insights
Prosper Menière observed that patients with his eponymous disease also suffered from migraine headaches. His historical writings reveal this early, though debated, connection between Menière
Area of Science:
- Otolaryngology
- Neurology
- Medical History
Background:
- Menière's disease is a disorder of the inner ear.
- The historical association between Menière's disease and migraine headaches is compelling.
- Prosper Menière's original observations are key to understanding this link.
Observation:
- Prosper Menière's writings detail patient symptoms, including tinnitus, hearing loss, vertigo, and migraine headaches.
- He noted a unique presentation of migraine headaches in his patient population.
- These observations were made in articles published shortly before his death.
Findings:
- Menière's work established a link between his eponymous disease and migraine headaches.
- His contemporaries largely dismissed this association.
- Analysis of his original texts supports the interpretation of these findings.
Implications:
- The historical connection between Menière's disease and migraine headaches continues to be a subject of scientific discussion.
- Understanding Menière's original insights provides historical context for current research.
- This highlights the enduring legacy of Prosper Menière's clinical observations.
More Related Videos
Related Concept Videos
Equilibrium and Balance
Pathophysiology of Vomiting
Mitral Regurgitation II: Clinical Features and Diagnostic Tests
Mitral Valve Prolapse II: Assessment and Management
Viral Meningitis
Mitral Regurgitation I: Introduction

