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Updated: Mar 18, 2026

Diagonal Method to Measure Synergy Among Any Number of Drugs
Published on: June 21, 2018
Practice Gaps: Drug Reactions
1Department of Dermatology, Indiana University, 545 Barnhill Drive, Emerson Hall 139, Indianapolis, IN 46202, USA.
Abstract:
The term "drug reactions" is relevant to dermatology in three categories of reactions: cutaneous drug reactions without systemic features, cutaneous drug reactions with systemic features, and systemic drugs prescribed by the dermatologist with systematic adverse effects. This article uses examples from each of these categories to illustrate several important principles central to drug reaction diagnosis and management. The information presented will help clinicians attain the highest possible level of certainty before making clinical decisions.
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