Related Experiment Video
Updated: Mar 18, 2026

Inducing Meningococcal Meningitis Serogroup C in Mice via Intracisternal Delivery
Published on: November 5, 2019
Outbreak of Meningococcal Infection amongst Soldiers Deployed in Operations
A S Kushwaha1, S K Aggarwal2, M M Arora3
1Reader (Dept of Community Medicine), AFMC Pune-40.
Background:
Meningococcal infection may lead to life threatening meningitis and fulminant meningococcal sepsis. Sporadic cases of meningococcal infection have been reported in soldiers but no outbreak in soldiers has been reported earlier from India. This outbreak in soldiers serving in counter insurgency role under field setting was effectively controlled without compromising their operational commitment.
Methods:
This is an epidemiological investigation and control of an outbreak of meningococcal infection, bringing out the predisposing factors and highlighting the role of early diagnosis and management of cases. Mass chemoprophylaxis in contacts was used as an effective control measure in the absence of vaccine in this institution based outbreak.
Result:
Out of a total of 17 cases reported, 14 presented as meningitis and three as meningococcemia. Two cases of meningococcemia ended fatally. Serogroup A of Neisseria meningitidis was responsible for this outbreak. Gross over- crowding was the predisposing factor.
Conclusion:
An outbreak of meningococcal infection in soldiers deployed in counter- insurgency role was effectively contained using mass chemoprophylaxis in the absence of meningococcal vaccine.
Insights
An outbreak of meningococcal infection in Indian soldiers was controlled using mass chemoprophylaxis. This strategy proved effective in preventing further spread of the disease during a counter-insurgency operation.
Area of Science:
- Epidemiology
- Infectious Diseases
- Public Health
Background:
- Meningococcal infection poses a severe threat, potentially causing meningitis and sepsis.
- While sporadic cases occur in soldiers, no prior outbreaks were documented in India.
- This study addresses an outbreak in soldiers during a counter-insurgency operation.
Purpose of the Study:
- To investigate and control an outbreak of meningococcal infection in soldiers.
- To identify predisposing factors and emphasize early diagnosis and management.
- To evaluate control measures in a field setting without vaccine availability.
Main Methods:
- Epidemiological investigation and outbreak control measures were implemented.
- Mass chemoprophylaxis was administered to contacts.
- Early diagnosis and case management were prioritized.
Main Results:
- A total of 17 cases were reported, including 14 with meningitis and 3 with meningococcemia.
- Serogroup A of Neisseria meningitidis was identified as the causative agent.
- Overcrowding was identified as a significant predisposing factor, and two fatalities occurred.
Conclusions:
- The meningococcal infection outbreak in soldiers was successfully contained.
- Mass chemoprophylaxis was an effective control measure in the absence of a vaccine.
- The operational commitment of the soldiers was maintained during the outbreak control.
Related Concept Videos
Viral Meningitis
Investigation of Disease Outbreaks
Clinical Significance of Antibiotic Resistance
Mechanism of Antibiotic Resistance in MRSA
Infectious Diseases and Their Occurrence
Infection
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...

