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Updated: Mar 18, 2026

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Brain Infarct Segmentation and Registration on MRI or CT for Lesion-symptom Mapping
Published on: September 25, 2019
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Isolated left posterior insular infarction and convergent roles in verbal fluency, language, memory, and executive
Parunyou Julayanont1, Doungporn Ruthirago1, John C DeToledo1
1Department of Neurology, Texas Tech University Health Science Center, Lubbock, Texas.
Summary
Isolated strokes in the posterior insular cortex are rare. This case highlights cognitive impairments, specifically in verbal fluency, following such an event.
Area of Science:
- Neuroscience
- Neurology
- Cognitive Science
Background:
- The posterior insular cortex is a critical brain region involved in diverse cognitive and sensory functions.
- Ischemic stroke in the posterior insular cortex is an uncommon clinical presentation.
Observation:
- A patient presented with an isolated ischemic stroke affecting the left posterior insular cortex.
- The patient exhibited significant cognitive deficits upon evaluation.
Findings:
- The stroke resulted in impairments in both semantic and phonemic verbal fluency.
- This suggests a specific role of the posterior insular cortex in language processing and executive functions related to word retrieval.
Implications:
- Understanding the functional neuroanatomy of the insular cortex is crucial for interpreting complex cognitive deficits after stroke.
- This case underscores the potential for subtle yet significant cognitive impairments arising from rare stroke locations.
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