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Malignant metastatic carcinoid presenting as brain tumor
I Vijay Sundar1, S K Jain1, Dhrubajyoti Kurmi1
1Department of Neurosurgery, SMS Medical College, Jaipur, Rajasthan, India.
Asian Journal of Neurosurgery
|July 2, 2016
Summary
Brain metastases from carcinoid tumors are rare, especially presenting as the initial symptom. This case highlights the diagnostic and therapeutic challenges of neuroendocrine tumors metastasizing to the brain.
Area of Science:
- Neuro-oncology
- Endocrinology
- Pathology
Background:
- Carcinoid tumors, a type of neuroendocrine tumor, rarely metastasize to the brain.
- Brain metastases often present insidiously, making early diagnosis challenging.
Observation:
- A 60-year-old man presented with hemiparesis and imaging findings indicative of a brain tumor.
- Surgical resection revealed a metastatic malignant lesion of neuroendocrine origin.
- Primary tumor workup was negative, suggesting an unknown primary source.
Findings:
- Histopathology confirmed metastatic neuroendocrine carcinoma.
- The patient received adjuvant radiotherapy for the brain metastasis.
Implications:
- This case underscores the importance of considering rare metastatic etiologies in brain tumor diagnostics.
- Effective management requires a multidisciplinary approach, integrating neurosurgery, oncology, and endocrinology.
- Further research into the pathophysiology and treatment of neuroendocrine brain metastases is warranted.
