Related Experiment Videos
[Effectiveness of selected disinfectant and antiseptic preparations on potentially pathogenic micromycetes]
Abstract:
Using the contact test, the author investigated the antifungal efficiency of 13 disinfectants and antiseptic preparations (hydrogen peroxide, Persteril, Jodonal B, Jodisol, Chlordetal, Famosept-Super, Septonex, Ajatin, Cresolum saponatum, ethanol, Desident spray, chlorhexidine, Galli-Valerio solution) against 23 strains of eight genera of microscopic fungi (Absidia, Aspergillus, Candida, Geotrichum, Mucor, Rhizopus, Torulopsis and Trichosporon). The results revealed that filamentous fungi and among them in particular zygomycetes are more resistant against the above preparations than yeasts. The highest antifungal activity was observed in 5% Creolum saponatum and 1% and 2% Famosept Super. On the other hand, 3% H2O2, 5% Jodisol and 0.1% Chlorhexidine were almost ineffective. On investigations of the vitality of spores and fragments of the mycelium of the tested micromycetes the greatest resistance to desiccation was manifested by conidia and hyphae of aspergilli, the smallest one by blastopores of yeasts Candida albicans and Torulopsis glabrata.
Insights
This study tested 13 disinfectants against fungi, finding Cresolum saponatum and Famosept-Super most effective. Yeasts were more susceptible than filamentous fungi, with Aspergillus spores showing high desiccation resistance.
Area of Science:
- Mycology
- Antimicrobial agents
Context:
- Fungal infections pose significant health risks.
- Effective disinfection is crucial for infection control.
- Understanding disinfectant efficacy against diverse fungi is essential.
Purpose:
- To evaluate the antifungal efficiency of thirteen disinfectants and antiseptic preparations.
- To compare the susceptibility of various fungal genera (filamentous fungi and yeasts) to these agents.
- To assess the resistance of fungal spores and mycelial fragments to desiccation.
Summary:
- Thirteen disinfectants were tested against 23 fungal strains using the contact test.
- Cresolum saponatum (5%) and Famosept-Super (1-2%) exhibited the highest antifungal activity.
- Hydrogen peroxide (3%), Jodisol (5%), and chlorhexidine (0.1%) showed minimal effectiveness.
- Filamentous fungi, particularly zygomycetes, were more resistant than yeasts.
- Aspergillus spores and hyphae demonstrated the greatest resistance to desiccation, while Candida and Torulopsis yeast blastospores were least resistant.
Impact:
- Identifies potent antifungal disinfectants for clinical and laboratory use.
- Provides data on differential susceptibility of fungal types to disinfectants.
- Highlights the need for specific disinfectant selection based on fungal targets.
- Informs strategies for preventing fungal contamination and transmission.