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Metabolic syndrome and C reactive protein in patients undergoing angiography: Inevitable association?
Sandra Maria Barbalho1, Marcelo Dib Bechara2, Ricardo José Tofano2
1Department of Biochemistry and Cellular Biology - Medical School of Marília - UNIMAR, Av. Higino Muzzi Filho 1001, Marília, São Paulo, Brazil; Food and Technology School of Marília (FATEC), São Paulo, Brazil; Cardiac Surgery Unit and Hemodynamics - Medical School UNIMAR (UNIMAR Hospital), Av. Higino Muzzi Filho 1001, Marília, São Paulo, Brazil.
Background:
The Metabolic Syndrome (MS) is characterized by a set of risk factors, which causes metabolic and inflammatory changes that increase vascular risk and may promote the development of atherosclerosis. Changes in lifestyle are related to obesity and associated diseases such as hypertension, type 2 diabetes mellitus, MS and cardiovascular disease (CVD).
Aims:
This study aimed to evaluate the relationship of MS components and high sensitivity C Reactive Protein (hsCRP) in patients undergoing arteriography.
Methods:
A group of patients undergoing arteriography was recruited in order we could evaluate the metabolic profile, levels of hsCRP and number of obstructions in the arteries.
Results:
Most of our patients underwent arteriography are more likely to have hypertension, glucose intolerance, dyslipidemia, and central obesity, thus, MS is prevalent in this group. They also tend to exhibit higher values of hsCRP, lower values for the estimative of the size of the LDL-c particle and higher number of obstruction in the arteries.
Conclusion:
We may say that the improvement of the above parameters could reduce inflammation and oxidative stress and vascular damages what would extend life expectancy and quality of life of this group of patients.
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